100 Proof
100 Proof may refer to:
- 100° proof, alcohol proof
 - 100 Proof (film), 1997 film
 - 100 Proof (album), Kellie Pickler album
 - 100 Proof: The Hangover, Statik Selektah album
 - "100 Proof" (song), Kellie Pickler song
 - 100 Proof (Aged in Soul), an American funk/soul group