2-Bromothiophene
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| Names | |
|---|---|
| Preferred IUPAC name 2-Bromothiophene | |
| Other names 2-Thienyl bromide, 2BT | |
| Identifiers | |
3D model (JSmol) | |
| ChemSpider | |
| ECHA InfoCard | 100.012.454 |
| EC Number |
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PubChem CID | |
| UNII | |
CompTox Dashboard (EPA) | |
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| Properties | |
| C4H3BrS | |
| Molar mass | 163.03 g·mol−1 |
| Appearance | Colorless liquid |
| Density | 1.684 g/mL |
| Melting point | −10 °C (14 °F; 263 K) |
| Boiling point | 153.5 °C (308.3 °F; 426.6 K) |
| Immiscible | |
| Hazards | |
| Occupational safety and health (OHS/OSH): | |
Main hazards | N,Xi,Xn,T |
| GHS labelling: | |
    | |
| Danger | |
| H226, H300, H301, H310, H315, H318, H319, H330 | |
| P210, P233, P240, P241, P242, P243, P260, P262, P264, P270, P271, P280, P284, P301+P310, P302+P350, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P320, P321, P322, P330, P332+P313, P337+P313, P361, P362, P363, P370+P378, P403+P233, P403+P235, P405, P501 | |
| Flash point | 56 °C (133 °F; 329 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references | |
2-Bromothiophene is an organosulfur compound with the formula C4H3BrS. It is a colorless liquid. Unlike 3-bromothiophene, the 2-bromo isomer is prepared directly by partial bromination of thiophene. It is a precursor to several drugs, including tipepidine, ticlopidine, and clopidogrel.[1]
Safety
The LD50 is low, 200 – 250 mg/kg (oral, rat).[1]
References
- ^ a b Jonathan Swanston (2006). "Thiophene". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a26_793.pub2. ISBN 978-3-527-30673-2.