Acifran

Acifran
Names
IUPAC name
5-Methyl-4-oxo-5-phenyl-4,5-dihydro-2-furancarboxylic acid
Systematic IUPAC name
5-Methyl-4-oxo-5-phenyl-4,5-dihydro-2-furancarboxylic acid
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
KEGG
UNII
  • InChI=1S/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,1H3,(H,14,15)
    Key: DFDGRKNOFOJBAJ-UHFFFAOYSA-N
  • InChI=1/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,1H3,(H,14,15)
    Key: DFDGRKNOFOJBAJ-UHFFFAOYAE
  • CC1(C(=O)C=C(O1)C(=O)O)C2=CC=CC=C2
Properties
C12H10O4
Molar mass 218.208 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Acifran is a niacin receptor agonist.[1]

References

  1. ^ Jung, J. K.; Johnson, B. R.; Duong, T; Decaire, M; Uy, J; Gharbaoui, T; Boatman, P. D.; Sage, C. R.; Chen, R; Richman, J. G.; Connolly, D. T.; Semple, G (April 2007). "Analogues of acifran: agonists of the high and low affinity niacin receptors, GPR109a and GPR109b". J. Med. Chem. 50 (7): 1445–8. doi:10.1021/jm070022x. PMID 17358052.
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