| Title | Director | Cast | Genre | Notes |
| Safari | Terence Young | Victor Mature, Janet Leigh, John Justin | Adventure | Columbia. Co-production with the UK. |
| Santiago | Gordon Douglas | Alan Ladd, Rossana Podestà, Lloyd Nolan | Thriller | Warner Bros. |
| Scandal Incorporated | Edward Mann | Robert Hutton, Patricia Wright, Paul Richards | Crime | Republic |
| The Scarlet Hour | Michael Curtiz | Carol Ohmart, Tom Tryon, Jody Lawrence | Film noir | Paramount |
| Screaming Eagles | Charles F. Haas | Tom Tryon, Martin Milner, Jacqueline Beer | War | Allied Artists |
| The Search for Bridey Murphy | Noel Langley | Teresa Wright, Louis Hayward, Nancy Gates | Drama | Paramount |
| The Searchers | John Ford | John Wayne, Jeffrey Hunter, Vera Miles | Western | Warner Bros. Voted best American Western |
| Secret of Treasure Mountain | Seymour Friedman | Valerie French, Raymond Burr, William Prince | Western | Columbia |
| Serenade | Anthony Mann | Mario Lanza, Joan Fontaine, Sara Montiel | Musical | Warner Bros. |
| Seven Men from Now | Budd Boetticher | Randolph Scott, Gail Russell, Lee Marvin | Western | Warner Bros. |
| Shake, Rattle & Rock! | Edward L. Cahn | Mike Connors, Lisa Gaye, Sterling Holloway | Musical | AIP |
| The Sharkfighters | Jerry Hopper | Victor Mature, Karen Steele, James Olson | Adventure | United Artists |
| The She-Creature | Edward L. Cahn | Marla English, Chester Morris, Cathy Downs | Science fiction | AIP |
| Showdown at Abilene | Charles F. Haas | Jock Mahoney, Martha Hyer, Lyle Bettger | Western | Universal[4] |
| Singing in the Dark | Max Nosseck | Moishe Oysher, Phyllis Hill, Joey Adams | Drama | Independent |
| Slightly Scarlet | Allan Dwan | John Payne, Rhonda Fleming, Arlene Dahl | Film noir | RKO |
| The Solid Gold Cadillac | Richard Quine | Judy Holliday, Paul Douglas, Fred Clark | Comedy | Columbia |
| Somebody Up There Likes Me | Robert Wise | Paul Newman, Pier Angeli, Sal Mineo | Biography | MGM. Story of Rocky Graziano; won two Oscars |
| Stagecoach to Fury | William F. Claxton | Forrest Tucker, Mari Blanchard, Wallace Ford | Western | 20th Century Fox |
| Star in the Dust | Charles F. Haas | John Agar, Mamie Van Doren, Richard Boone | Western | Universal |
| The Steel Jungle | Walter Doniger | Perry Lopez, Beverly Garland, Walter Abel | Crime | Warner Bros. |
| Storm Center | Daniel Taradash | Bette Davis, Brian Keith, Kim Hunter | Drama | Columbia |
| A Strange Adventure | William Witney | Joan Evans, Ben Cooper, Marla English | Drama | Republic |
| Strange Intruder | Irving Rapper | Ida Lupino, Edmund Purdom, Ann Harding | Drama | Allied Artists |
| Stranger at My Door | William Witney | Macdonald Carey, Patricia Medina, Skip Homeier | Western | Republic |
| The Swan | Charles Vidor | Grace Kelly, Louis Jourdan, Alec Guinness | Romance | MGM; remake of 1925 film |
| Tea and Sympathy | Vincente Minnelli | Deborah Kerr, John Kerr, Leif Erickson | Drama | MGM; based on the play |
| The Teahouse of the August Moon | Daniel Mann | Marlon Brando, Glenn Ford, Machiko Kyō | Comedy | MGM; based on the play |
| Teenage Rebel | Edmund Goulding | Ginger Rogers, Michael Rennie, Mildred Natwick | Drama | 20th Century Fox. 2 Oscar nominations |
| The Ten Commandments | Cecil B. DeMille | Charlton Heston, Yul Brynner, Edward G. Robinson | Drama | Paramount. Remake of 1923 film; 7 Oscar nominations; DeMille's final film |
| Tension at Table Rock | Charles Marquis Warren | Dorothy Malone, Richard Egan, Cameron Mitchell | Western | RKO |
| Terror at Midnight | Franklin Adreon | Scott Brady, Joan Vohs, Frank Faylen | Crime | Republic |
| That Certain Feeling | Melvin Frank | Bob Hope, Eva Marie Saint, Pearl Bailey | Comedy | Paramount |
| There's Always Tomorrow | Douglas Sirk | Barbara Stanwyck, Fred MacMurray, Joan Bennett | Drama | Universal. Remake of 1934 film |
| These Wilder Years | Roy Rowland | James Cagney, Barbara Stanwyck, Walter Pidgeon | Drama | MGM |
| Three Bad Sisters | Gilbert Kay | Marla English, John Bromfield, Kathleen Hughes | Drama | United Artists |
| Three Brave Men | Philip Dunne | Ray Milland, Ernest Borgnine, Nina Foch | Drama | 20th Century Fox |
| The Three Outlaws | Sam Newfield | Neville Brand, Alan Hale Jr., Bruce Bennett | Western | Independent |
| Thunder Over Arizona | Joseph Kane | Skip Homeier, Kristine Miller, George Macready | Western | Republic |
| Time Table | Mark Stevens | Mark Stevens, Felicia Farr, Marianne Stewart | Film noir | United Artists |
| Toward the Unknown | Mervyn LeRoy | William Holden, Virginia Leith, Lloyd Nolan | Drama | Warner Bros. |
| The Toy Tiger | Jerry Hopper | Laraine Day, Jeff Chandler, Cecil Kellaway | Comedy | Universal |
| Trapeze | Carol Reed | Burt Lancaster, Tony Curtis, Gina Lollobrigida | Drama | United Artists; Silver Bear award for Lancaster |
| Tribute to a Bad Man | Robert Wise | James Cagney, Stephen McNally, Don Dubbins | Western | MGM |
| The Unguarded Moment | Harry Keller | Esther Williams, George Nader, John Saxon | Film noir | Universal |
| Uranium Boom | William Castle | Dennis Morgan, Patricia Medina, William Talman | Adventure | Columbia |
| The Vagabond King | Michael Curtiz | Kathryn Grayson, Rita Moreno, Oreste Kirkop | Musical | Paramount; Grayson's final film |
| The Violent Years | William Morgan | Jean Moorhead, Barbara Weeks, I. Stanford Jolley | Crime | Independent |
| Walk the Proud Land | Jesse Hibbs | Audie Murphy, Anne Bancroft, Pat Crowley | Western | Universal |
| War and Peace | King Vidor | Audrey Hepburn, Henry Fonda, Mel Ferrer | Historical | Paramount. Based on Leo Tolstoy novel; 3 Oscar nominations |
| The Werewolf | Fred F. Sears | Don Megowan, Joyce Holden, Harry Lauter | Horror | Columbia |
| Westward Ho the Wagons! | William Beaudine | Fess Parker, Kathleen Crowley, John War Eagle | Western | Disney |
| Wetbacks | Hank McCune | Lloyd Bridges, Nancy Gates, Barton MacLane | Crime | Independent |
| When Gangland Strikes | R. G. Springsteen | Raymond Greenleaf, Marjie Millar, John Hudson | Crime | Republic |
| While the City Sleeps | Fritz Lang | Dana Andrews, Vincent Price, Ida Lupino | Film noir | RKO |
| The White Squaw | Ray Nazarro | David Brian, May Wynn, William Bishop | Western | Columbia |
| The Wild Party | Harry Horner | Anthony Quinn, Carol Ohmart, Arthur Franz | Film noir | United Artists |
| A Woman's Devotion | Paul Henreid | Janice Rule, Ralph Meeker, Rosenda Monteros | Film noir | Republic |
| The Women of Pitcairn Island | Jean Yarbrough | James Craig, Lynn Bari, Sue England | Adventure | 20th Century Fox |
| World in My Corner | Jesse Hibbs | Audie Murphy, Barbara Rush, Jeff Morrow | Sports | Universal |
| World Without End | Edward Bernds | Hugh Marlowe, Nancy Gates, Rod Taylor | Science fiction | Allied Artists |
| Written on the Wind | Douglas Sirk | Rock Hudson, Lauren Bacall, Dorothy Malone | Drama | Universal. Oscar for Malone |
| The Wrong Man | Alfred Hitchcock | Henry Fonda, Vera Miles, Anthony Quayle | Film noir | Warner Bros. |
| Yaqui Drums | Jean Yarbrough | Rod Cameron, Mary Castle, J. Carrol Naish | Western | Allied Artists |
| You Can't Run Away from It | Dick Powell | June Allyson, Jack Lemmon, Charles Bickford | Musical | Columbia |
| The Young Guns | Albert Band | Russ Tamblyn, Gloria Talbott, Perry Lopez | Western | Allied Artists |