List of Sites of Special Scientific Interest in Nithsdale
The following is a list of Sites of Special Scientific Interest in the Nithsdale Area of Search. For other areas, see List of SSSIs by Area of Search.
- Back Wood
 - Black Loch
 - Carron Water and Hapland Burn
 - Chanlockfoot
 - Coshogle Wood
 - Kirkconnell Flow
 - Lag Meadow
 - Lagrae Burn
 - Leadhills-Wanlockhead
 - Locharbriggs Quarry
 - Longbridge Muir
 - Mennock Water
 - North Lowther Uplands
 - Polhote and Polneul Burns
 - River Nith at Drumlanrig Bridge De-notified (confirmed) on 17 November 2011
 - Shiel Dod
 - Stenhouse Wood
 - Tynron Juniper Wood
 - Upper Solway Flats and Marshes