Mother of Cities
Mother of Cities may refer to:
- Mecca, is the capital of Mecca Province in western Saudi Arabia, the holiest city in Islam, and is referenced in the Quran as the 'mother of cities'. See Quran 6:92, 42:7.
 - Asunción, capital and largest city of Paraguay.
 - Balkh, among the oldest cities of Afghanistan.
 - Prague, capital and largest city of the Czech Republic.
 - Santiago del Estero, oldest city of Argentina.