Piloty's acid

Piloty's acid
Names
	Preferred IUPAC name N-Hydroxybenzenesulfonamide
	Other names benzenesulfohydroxamic acid
Identifiers
CAS Number	599-71-3;
ChEMBL	ChEMBL55310;
ChemSpider	62255;
ECHA InfoCard	100.009.068
EC Number	209-973-8;
PubChem CID	69033;
UNII	C64L4UMH19;
CompTox Dashboard (EPA)	DTXSID4060521 ;
	InChI InChI=1S/C6H7NO3S/c8-7-11(9,10)6-4-2-1-3-5-6/h1-5,7-8H Key: BRMDATNYMUMZLN-UHFFFAOYSA-N;
Properties
Chemical formula	C6H7NO3S
Molar mass	173.19 g·mol−1
Appearance	white solid
Melting point	186 °C (367 °F; 459 K)
Acidity (pKa)	9.29
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Piloty's acid is an organic compound with the formula C₆H₅SO₂N(H)OH. A white solid, it is the benzenesulfonyl derivative of hydroxylamine. It is one of the main reagents used to generate nitroxyl (HNO), a highly reactive species that is implicated in a some chemical and biochemical reactions.^[2]

References

^ Lester Packer (1999). Nitric Oxide: Biological and antioxidant activities. Gulf Professional Publishing. p. 286. ISBN 978-0-12-182202-6.
^ Hughes, Martin N.; Cammack, Richard (1999). "Synthesis, chemistry, and Applications of Nitroxyl Ion Releasers Sodium Trioxodinitrate or Angeli's Salt and Piloty's Acid". Nitric Oxide, Part C: Biological and Antioxidant Activities. Methods in Enzymology. Vol. 301. pp. 279–287. doi:10.1016/S0076-6879(99)01092-7. ISBN 978-0-12-182202-6. PMID 9919577.

[Packer1999-1] Lester Packer (1999). Nitric Oxide: Biological and antioxidant activities. Gulf Professional Publishing. p. 286. ISBN 978-0-12-182202-6.

[2] Hughes, Martin N.; Cammack, Richard (1999). "Synthesis, chemistry, and Applications of Nitroxyl Ion Releasers Sodium Trioxodinitrate or Angeli's Salt and Piloty's Acid". Nitric Oxide, Part C: Biological and Antioxidant Activities. Methods in Enzymology. Vol. 301. pp. 279–287. doi:10.1016/S0076-6879(99)01092-7. ISBN 978-0-12-182202-6. PMID 9919577.

[1]

[2]

See also

References