Streptomyces toxytricini

Streptomyces toxytricini
Scientific classification Edit this classification
Domain: Bacteria
Kingdom: Bacillati
Phylum: Actinomycetota
Class: Actinomycetes
Order: Streptomycetales
Family: Streptomycetaceae
Genus: Streptomyces
Species:
S. toxytricini
Binomial name
Streptomyces toxytricini
Preobrazhenskaya & Sveshnikova 1957

Streptomyces toxytricini is a Gram-positive bacterium belonging to the genus Streptomyces. It produces the pancreatic lipase inhibitor lipstatin,[1] of which the antiobesity drug orlistat is a derivative.[2]

References

  1. ^ Weibel E, Hadvary P, Hochuli E, Kupfer E, Lengsfeld H (1987). "Lipstatin, an inhibitor of pancreatic lipase, produced by Streptomyces toxytricini. I. Producing organism, fermentation, isolation and biological activity". J Antibiot (Tokyo). 40 (8): 1081–5. doi:10.7164/antibiotics.40.1081. PMID 3680018.
  2. ^ Barbier P, Schneider F (1987). "Syntheses of tetrahydrolipstatin and absolute configuration of tetrahydrolipstatin and lipstatin". Helvetica Chimica Acta. 70 (1): 196–202. doi:10.1002/hlca.19870700124.

Further reading


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