Alginate synthase
| alginate synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.4.1.33 | ||||||||
| CAS no. | 37257-31-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, an alginate synthase (EC 2.4.1.33) is an enzyme that catalyzes the chemical reaction
- GDP-D-mannuronate + (alginate)n GDP + (alginate)n+1
Thus, the two substrates of this enzyme are GDP-D-mannuronate and (alginate)n, whereas its two products are GDP and (alginate)n+1.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-D-mannuronate:alginate D-mannuronyltransferase. This enzyme is also called mannuronosyl transferase. This enzyme participates in fructose and mannose metabolism.
References
- Lin TY, Hassid WZ (1966). "Pathway of algnic acid synthesis in the marine brown alga, Fucus gardneri Silva". J. Biol. Chem. 241 (22): 5284–97. doi:10.1016/S0021-9258(18)96429-X. PMID 5954796.