Calfactant

Calfactant
Clinical data
Trade namesInfasurf
Pregnancy
category
  • N
ATC code
  • none
Legal status
Legal status
Identifiers
CAS Number
ChemSpider
  • none
UNII
ChEMBL
 ☒NcheckY (what is this?)  (verify)

Calfactant, also known as Infasurf,[1] is an intratracheal suspension derived from the natural surfactant in calf lungs. It is used in premature infants with lung surfactant deficiency that causes infant respiratory distress syndrome (IRDS).[2]

Mechanism of action

Lung surfactant is essential for effective ventilation as it modifies alveolar surface tension.[3] IRDS is caused by a lung surfactant deficiency. Calfactant serves as a substitute for the natural surfactant.[2]

References

  1. ^ "Infasurf". Archived from the original on 2011-12-09. Retrieved 2011-12-16.
  2. ^ a b Drugs.com: "Calfactant". Drugs.com.
  3. ^ Schurch S, Lee M, Gehr P (1992). "Pulmonary surfactant: Surface properties and function of alveolar and airway surfactant". Pure and Applied Chemistry. 64 (11): 1745–1750. doi:10.1351/pac199264111745. S2CID 97007574.
This article is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.