| Year | Title | Creators | Ref. |
| 1990s |
| 1988 | Concrete (Dark Horse Comics) | Paul Chadwick | [2] |
| Grendel (Comico) | Matt Wagner, Arnold Pander, Jacob Pander, and Jay Geldof |
| Love and Rockets (Fantagraphics) | Jaime Hernandez and Gilbert Hernandez |
| Zot! (Eclipse Comics) | Scott McCloud |
| 1989 | Concrete (Dark Horse Comics) | Paul Chadwick | [3] |
| Love and Rockets (Fantagraphics) | Jaime Hernandez and Gilbert Hernandez |
| Nexus (First Comics) | Mike Baron, Steve Rude and various artists |
| "Omaha" the Cat Dancer (Kitchen Sink Press) | Reed Waller and Kate Worley |
| The Question (DC Comics) | Dennis O'Neil, Denys Cowan, and Rick Magyar |
| 1990s |
| 1990 | There was no Eisner Award ceremony, or awards distributed, in 1990, due to widespread balloting mix-ups.[4] |
| 1991 | The Sandman (DC Comics) | Neil Gaiman and various artists | [5] |
| Cerebus the Aardvark (Aardvark-Vanaheim) | Dave Sim, Gerhard |
| Eightball (Fantagraphics) | Dan Clowes |
| Miracleman (Eclipse Comics) | Alan Moore and various artists |
| Yummy Fur (Vortex Comics) | Chester Brown |
| Zot! (Eclipse Comics) | Scott McCloud |
| 1992 | The Sandman (DC Comics) | Neil Gaiman and various artists | [6] |
| Cerebus the Aardvark (Aardvark-Vanaheim) | Dave Sim, Gerhard |
| Doom Patrol (DC Comics) | Grant Morrison, Richard Case and various artists |
| Flaming Carrot (Renegade Press) | Bob Burden |
| Groo the Wanderer (Marvel Comics/Epic Comics) | Mark Evanier and Sergio Aragonés |
| Miracleman (Eclipse Comics) | Neil Gaiman, Mark Buckingham, and Sam Parsons |
| The Incredible Hulk (Marvel Comics) | Peter David and Dale Keown |
| Love and Rockets (Fantagraphics) | Jaime Hernandez and Gilbert Hernandez |
| Yummy Fur (Drawn & Quarterly) | Chester Brown |
| 1993 | The Sandman (DC Comics) | Neil Gaiman and various artists | [7] |
| Cerebus the Aardvark (Aardvark-Vanaheim) | Dave Sim, Gerhard |
| Hate (Fantagraphics) | Peter Bagge |
| Hellblazer (DC Comics) | Garth Ennis and various artists |
| Love and Rockets (Fantagraphics) | Gilbert Hernandez and Jaime Hernandez |
| Real Stuff (Fantagraphics) | Dennis Eichhorn and others |
| Shade, the Changing Man (DC Comics) | Peter Milligan and various artists |
| 1994 | Bone (Cartoon Books) | Jeff Smith | [8] |
| Cerebus the Aardvark (Aardvark-Vanaheim) | Dave Sim and Gerhard |
| Hellblazer (DC Comics/Vertigo Comics) | Garth Ennis and Steve Dillon |
| The Sandman (DC Comics/Vertigo Comics) | Neil Gaiman |
| Shade, the Changing Man (DC Comics/Vertigo Comics) | Peter Milligan and Chris Bachalo |
| 1995 | Bone (Cartoon Books) | Jeff Smith | [9] |
| The Books of Magic (DC Comics/Vertigo Comics) | John Ney Rieber, Gary Amaro, and Peter Gross |
| Icon (Milestone) | Dwayne McDuffie and M. D. Bright |
| Starman (DC Comics) | James Robinson and Tony Harris |
| Strangers in Paradise (Abstract Studio) | Terry Moore |
| Uncle Scrooge (Gladstone Publishing) | Don Rosa and others |
| 1996 | Acme Novelty Library (Fantagraphics) | Chris Ware | [10] |
| Astro City (Jukebox Productions/Image Comics) | Kurt Busiek and Brent Anderson |
| Preacher (DC Comics/Vertigo Comics) | Garth Ennis and Steve Dillon |
| Strangers in Paradise (Abstract Studio) | Terry Moore |
| Stray Bullets (El Capitan Books) | David Lapham |
| 1997 | Astro City (Jukebox Productions/Homage Comics) | Kurt Busiek, Brent Anderson, and Will Blyberg | [11] |
| Akiko (Sirius Entertainment) | Mark Crilley |
| Kane (Dancing Elephant Press) | Paul Grist |
| Starman (DC Comics) | James Robinson, Tony Harris, and Wade Von Grawbadger |
| Strangehaven (Abiogenesis Press) | Gary Spencer Millidge |
| Strangers in Paradise (Abstract Studio/Homage Comics) | Terry Moore |
| 1998 | Astro City (Jukebox Productions/Homage Comics) | Kurt Busiek, Brent Anderson, and Will Blyberg | [12] |
| Acme Novelty Library (Fantagraphics) | Chris Ware |
| Akiko (Sirius Entertainment) | Mark Crilley |
| Bone (Cartoon Books) | Jeff Smith |
| Leave It to Chance (Homage Comics) | James Robinson and Paul Smith |
| Preacher (DC Comics/Vertigo Comics) | Garth Ennis and Steve Dillon |
| 1999 | Preacher (DC Comics/Vertigo Comics) | Garth Ennis and Steve Dillon | [13] |
| Avengers (Marvel Comics) | Kurt Busiek, George Pérez, and Al Vey |
| Kurt Busiek's Astro City (Homage Comics/WildStorm/Image Comics) | Kurt Busiek, Brent Anderson, and Will Blyberg |
| Sandman Mystery Theatre (DC Comics/Vertigo Comics) | Steven T. Seagle and Guy Davis |
| Transmetropolitan (DC Comics/Vertigo Comics) | Warren Ellis, Darick Robertson, and Rodney Ramos |
| 2000s |
| 2000 | Acme Novelty Library (Fantagraphics) | Chris Ware | [14] |
| Planetary (DC Comics/WildStorm) | Warren Ellis and John Cassaday |
| Preacher (DC Comics/Vertigo Comics) | Garth Ennis and Steve Dillon |
| Promethea (America's Best Comics) | Alan Moore, J. H. Williams III, and Mick Gray |
| Top 10 (America's Best Comics) | Alan Moore, Gene Ha, and Zander Cannon |
| Transmetropolitan (DC Comics/Vertigo Comics) | Warren Ellis, Darick Robertson, and Rodney Ramos |
| 2001 | Top 10 (America's Best Comics) | Alan Moore, Gene Ha, and Zander Cannon | [15] |
| Age of Bronze (Image Comics) | Eric Shanower |
| Berlin (Drawn & Quarterly) | Jason Lutes |
| Eagle: The Making of an Asian-American President (Viz Media) | Kaiji Kawaguchi |
| Promethea (America's Best Comics) | Alan Moore, J. H. Williams III, and Mick Gray |
| 2002 | 100 Bullets (DC Comics/Vertigo Comics) | Brian Azzarello and Eduardo Risso | [16] |
| Finder (Lightspeed Press) | Carla Speed McNeil |
| Planetary (DC Comics/WildStorm) | Warren Ellis and John Cassaday |
| Queen & Country (Oni Press) | Greg Rucka and Steve Rolston |
| Ruse (CrossGen) | Mark Waid, Butch Guice, and Mike Perkins |
| 2003 | Daredevil (Marvel Comics) | Brian Michael Bendis and Alex Maleev | [17] |
| Age of Bronze (Image Comics) | Eric Shanower |
| Fables (DC Comics/Vertigo Comics) | Bill Willingham, Lan Medina, Mark Buckingham, and Steve Leialoha |
| Louis Riel (Drawn & Quarterly) | Chester Brown |
| Strangers in Paradise (Abstract Studio) | Terry Moore |
| True Story, Swear to God (Clib's Boy Comics) | Tom Beland |
| 2004 | 100 Bullets (DC Comics/Vertigo Comics) | Brian Azzarello and Eduardo Risso | [18] |
| Alias (Marvel Comics) | Brian Michael Bendis and Michael Gaydos |
| Daredevil (Marvel Comics) | Brian Michael Bendis, Alex Maleev, and David W. Mack |
| The Goon (Dark Horse Comics) | Eric Powell |
| Gotham Central (DC Comics) | Ed Brubaker, Greg Rucka, Michael Lark, Brian Hurtt, and Stefano Gaudiano |
| Queen & Country (Oni Press) | Greg Rucka, Jason Alexander, Carla Speed McNeil, and Mike Hawthorne |
| 2005 | The Goon (Dark Horse Comics) | Eric Powell | [19] |
| Astonishing X-Men (Marvel Comics) | Joss Whedon and John Cassaday |
| Ex Machina (WildStorm/DC Comics) | Brian K. Vaughan, Tony Harris, and Tom Fesiter |
| Stray Bullets (El Capitan Books) | David Lapham |
| Y: The Last Man (Vertigo Comics/DC Comics) | Brian K. Vaughan, Pia Guerra, and José Marzan Jr. |
| 2006 | Astonishing X-Men (Marvel Comics) | Joss Whedon and John Cassaday | [20] |
| Age of Bronze (Image Comics) | Eric Shanower |
| Ex Machina (WildStorm/DC Comics) | Brian K. Vaughan, Tony Harris, and Tom Feister |
| Fell (Image Comics) | Warren Ellis and Ben Templesmith |
| Rocketo (Speakeasy Comics) | Frank Espinosa |
| True Story, Swear to God (Clib's Boy Comics) | Tom Beland |
| 2007 | All-Star Superman (DC Comics) | Grant Morrison and Frank Quitely | [21] |
| Captain America (Marvel Comics) | Ed Brubaker and Steve Epting |
| Daredevil (Marvel Comics) | Ed Brubaker, Michael Lark, and Stefano Gaudiano |
| Monster (Viz Media) | Naoki Urasawa |
| The Walking Dead (Image Comics) | Robert Kirkman and Charlie Adlard |
| Young Avengers (Marvel Comics) | Allan Heinberg, Jim Cheung, and various inkers |
| 2008 | Y: The Last Man (Vertigo Comics/DC Comics) | Brian K. Vaughan, Pia Guerra, and Jose Marzan, Jr. | [22] |
| The Boys (Dynamite Entertainment) | Garth Ennis and Darick Robertson |
| Buffy the Vampire Slayer Season Eight (Dark Horse Comics) | Joss Whedon, Brian K. Vaughan, Georges Jeanty, and Andy Owens |
| Monster (Viz Media) | Naoki Urasawa |
| The Spirit (DC Comics) | Darwyn Cooke |
| 2009 | All-Star Superman (DC Comics) | Grant Morrison and Frank Quitely | [23][24] |
| Fables (Vertigo Comics/DC Comics) | Bill Willingham, Mark Buckingham, Steve Leialoha, Niko Henrichon, Andrew Pepoy, and Peter Gross |
| Monster (Viz Media) | Naoki Urasawa |
| Thor (Marvel Comics) | J. Michael Straczynski, Olivier Coipel, Mark Morales, and various |
| Usagi Yojimbo (Dark Horse Comics) | Stan Sakai |
| 2010s |
| 2010 | The Walking Dead (Image Comics) | Robert Kirkman and Charlie Adlard | [25][26] |
| Fables (Vertigo Comics/DC Comics) | Bill Willingham, Mark Buckingham, Steve Leialoha, Andrew Pepoy et al. |
| Irredeemable (Boom! Studios) | Mark Waid and Peter Krause |
| 20th Century Boys (Viz Media) | Naoki Urasawa |
| The Unwritten (Vertigo Comics/DC Comics) | Mike Carey and Peter Gross |
| 2011 | Chew (Image Comics) | John Layman and Rob Guillory | [27][28] |
| Echo (Abstract Studio) | Terry Moore |
| Locke & Key (IDW Publishing) | Joe Hill and Gabriel Rodriguez |
| Morning Glories (Shadowline/Image Comics) | Nick Spencer and Joe Eisma |
| 20th Century Boys (Viz Media) | Naoki Urasawa |
| Scalped (Vertigo Comics/DC Comics) | Jason Aaron and R. M. Guéra |
| 2012 | Daredevil (Marvel Comics) | Mark Waid, Marcos Martín, Paolo Rivera, and Joe Rivera | [29][28] |
| 20th Century Boys (Viz Media) | Naoki Urasawa |
| Rachel Rising (Abstract Studio) | Terry Moore |
| Ultimate Comics: Spider-Man (Marvel Comics) | Brian Michael Bendis and Sara Pichelli |
| Usagi Yojimbo (Dark Horse Comics) | Stan Sakai |
| 2013 | Saga (Image Comics) | Brian K. Vaughan and Fiona Staples | [30][28] |
| Fatale (Image Comics) | Ed Brubaker and Sean Phillips |
| Hawkeye (Marvel Comics) | Matt Fraction and David Aja |
| The Manhattan Projects (Image Comics) | Jonathan Hickman and Nick Pitarra |
| Prophet (Image Comics) | Brandon Graham and Simon Roy |
| 2014 | Saga (Image Comics) | Brian K. Vaughan and Fiona Staples | [31][28] |
| East of West (Image Comics) | Jonathan Hickman and Nick Dragotta |
| Hawkeye (Marvel Comics) | Matt Fraction and David Aja |
| Nowhere Men (Image Comics) | Eric Stephenson and Nate Bellegarde |
| Sex Criminals (Image Comics) | Matt Fraction and Chip Zdarsky |
| 2015 | Saga (Image Comics) | Brian K. Vaughan and Fiona Staples | [32][28] |
| Astro City (Vertigo Comics) | Kurt Busiek and Brent Anderson |
| Bandette (MonkeyBrain Books) | Paul Tobin and Colleen Coover |
| Hawkeye (Marvel Comics) | Matt Fraction and David Aja |
| Southern Bastards (Image Comics) | Jason Aaron and Jason Latour |
| The Walking Dead (Image Comics/Skybound Entertainment) | Robert Kirkman, Charlie Adlard, and Stefano Gaudiano |
| 2016 | Southern Bastards (Image Comics) | Jason Aaron and Jason Latour | [33][28] |
| Bandette (MonkeyBrain Books) | Paul Tobin and Colleen Coover |
| Giant Days (Boom! Studios) | John Allison, Lissa Treiman, and Max Sarin |
| Invincible (Image Comics/Skybound Entertainment) | Robert Kirkman, Ryan Ottley, and Cliff Rathburn |
| Silver Surfer (Marvel Comics) | Dan Slott and Mike Allred |
| 2017 | Saga (Image Comics) | Brian K. Vaughan and Fiona Staples | [34][28] |
| Astro City (Vertigo Comics/DC Comics) | Kurt Busiek and Brent Anderson |
| Kill or Be Killed (Image Comics) | Ed Brubaker and Sean Phillips |
| The Mighty Thor (Marvel Comics) | Jason Aaron and Russell Dauterman |
| Paper Girls (Image Comics) | Brian K. Vaughan and Cliff Chiang |
| 2018 | Monstress (Image Comics) | Marjorie Liu and Sana Takeda | [35][28] |
| Black Hammer (Dark Horse Comics) | Jeff Lemire, Dean Ormston, and David Rubín |
| Giant Days (Boom! Studios) | John Allison, Max Sarin, and Liz Fleming |
| Hawkeye (Marvel Comics) | Kelly Thompson, Leonardo Romero, and Mike Walsh |
| The Wicked + The Divine (Image Comics) | Kieron Gillen and Jamie McKelvie |
| 2019 | Giant Days (Boom! Studios) | John Allison, Max Sarin, and Julia Madrigal | [36] |
| Batman (DC Comics) | Tom King et al. |
| Black Hammer: Age of Doom (Dark Horse Comics) | Jeff Lemire, Dean Ormston, and Rich Tommaso |
| Gasolina (Skybound Entertainment/Image Comics) | Sean Mackiewicz and Niko Walter |
| The Immortal Hulk (Marvel Comics) | Al Ewing, Joe Bennett, and Ruy José |
| Runaways (Marvel Comics) | Rainbow Rowell and Kris Anka |
| 2020s |
| 2020 | Bitter Root (Image Comics) | David F. Walker, Chuck Brown, and Sanford Greene | [37][38] |
| Criminal (Image Comics) | Ed Brubaker and Sean Phillips |
| Crowded (Image Comics) | Christopher Sebela, Ro Stein, and Ted Brandt |
| Daredevil (Marvel Comics) | Chip Zdarsky and Marco Checchetto |
| The Dreaming (DC Comics) | Simon Spurrier, Bilquis Evely et al. |
| The Immortal Hulk (Marvel Comics) | Al Ewing, Joe Bennett, and Ruy José et al. |
| 2021 | Usagi Yojimbo (IDW Publishing) | Stan Sakai | [39][40] |
| Bitter Root (Image Comics) | David F. Walker, Chuck Brown, and Sanford Greene |
| Daredevil (Marvel Comics) | Chip Zdarsky and Marco Checchetto |
| The Department of Truth (Image Comics) | James Tynion IV and Martin Simmonds |
| Gideon Falls (Image Comics) | Jeff Lemire and Andrea Sorrentino |
| Stillwater (Image Comics/Skybound Entertainment) | Chip Zdarsky and Ramón K. Pérez |
| 2022 | Bitter Root (Image Comics) [note 1] | David F. Walker, Chuck Brown, and Sanford Greene | [41][42] |
| Something is Killing the Children (Boom! Studios) [note 1] | James Tynion IV and Werther Dell'Edera |
| The Department of Truth (Image Comics) | James Tynion IV and Martin Simmonds |
| The Immortal Hulk (Marvel Comics) | Al Ewing, Joe Bennett, et al. |
| Nightwing (DC Comics) | Tom Taylor and Bruno Redondo |
| 2023 | Nightwing (DC Comics) | Tom Taylor and Bruno Redondo | [43][44] |
| Daredevil (Marvel Comics) | Chip Zdarsky, Marco Checchetto, and Rafael de Latorre |
| The Department of Truth (Image Comics) | James Tynion IV and Martin Simmonds |
| Killadelphia (Image Comics) | Rodney Barnes and Jason Shawn Alexander |
| The Nice House on the Lake (DC Comics) | James Tynion IV and Alvaro Martinez Bueno |
| She-Hulk (Marvel Comics) | Rainbow Rowell, Rogê Antônio, Luca Maresca, and Takeshi Miyazawa |
| 2024 | Transformers (Image Comics/Skybound Entertainment) | Daniel Warren Johnson | [45] |
| Birds of Prey (DC Comics) | Kelly Thompson and Leonardo Basto Romero |
| Nightwing (DC Comics) | Tom Taylor and Bruno Redondo |
| Shazam! (DC Comics) | Mark Waid and Dan Mora |
| Wonder Woman (DC Comics) | Tom King and Daniel Sampere |