Etilefrine pivalate

Etilefrine pivalate
Clinical data
Other names	Etilephrine pivalate; Ethylnorphenylephrine pivalate; Pivalyletilefrine; 3,β-Dihydroxy-N-ethylphenethylamine 3-pivalate
Identifiers
	IUPAC name [3-[2-(ethylamino)-1-hydroxyethyl]phenyl] 2,2-dimethylpropanoate;
CAS Number	85750-39-6;
PubChem CID	157211;
ChemSpider	138362;
UNII	3RLD929C4S;
ChEBI	CHEBI:134737;
ChEMBL	ChEMBL2105571;
CompTox Dashboard (EPA)	DTXSID10868931 ;
Chemical and physical data
Formula	C15H23NO3
Molar mass	265.353 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCNCC(C1=CC(=CC=C1)OC(=O)C(C)(C)C)O;
	InChI InChI=1S/C15H23NO3/c1-5-16-10-13(17)11-7-6-8-12(9-11)19-14(18)15(2,3)4/h6-9,13,16-17H,5,10H2,1-4H3; Key:DRMHNJGOEAYOIZ-UHFFFAOYSA-N;

Etilefrine pivalate INNTooltip International Nonproprietary Name; developmental code name K-30052) is a sympathomimetic agent which was never marketed.^[1]^[2] It is the 3-pivalate ester of etilefrine (ethylnorphenylephrine) and has much greater lipophilicity than etilefrine.^[1]^[3] Some related compounds include pivenfrine (phenylephrine pivalate) and dipivefrine (epinephrine dipivalate), which were developed as mydriatic agents.^[1]

References

^ ^a ^b ^c Elks J (2014). "A-00272: 2-Amino-1-(3-hydroxyphenyl)ethanol: Etilefrine pivalate". The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. pp. 61, 455, 1001. ISBN 978-1-4757-2085-3. Retrieved 1 September 2024.
^ Morton IK, Hall JM (2012). "Etilefrine". Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Netherlands. p. 116. ISBN 978-94-011-4439-1. Retrieved 2024-09-01.
^ "Etilefrine pivalate". PubChem. U.S. National Library of Medicine. Retrieved 1 September 2024.