Jedi2

Jedi2
Names
Preferred IUPAC name
2-methyl-5-thiophen-2-ylfuran-3-carboxylic acid
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
  • InChI=1S/C10H8O3S/c1-6-7(10(11)12)5-8(13-6)9-3-2-4-14-9/h2-5H,1H3,(H,11,12)
    Key: YXDCRSXNEOKXDE-UHFFFAOYSA-N
  • CC1=C(C=C(O1)C2=CC=CS2)C(=O)O
Properties
C10H8O3S
Molar mass 208.23 g·mol−1
Hazards
GHS labelling:[1]
GHS07: Exclamation mark
Warning
H302, H315, H317, H319
P261, P264, P264+P265, P270, P272, P280, P301+P317, P302+P352, P305+P351+P338, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Jedi2 is a chemical compound which acts as an agonist for the mechanosensitive ion channel PIEZO1, and is used in research into the function of touch perception.[1][2]

See also

References

  1. ^ Wang Y, Chi S, Guo H, Li G, Wang L, Zhao Q, et al. (April 2018). "A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel". Nature Communications. 9 (1): 1300. Bibcode:2018NatCo...9.1300W. doi:10.1038/s41467-018-03570-9. PMC 5880808. PMID 29610524.
  2. ^ Fang XZ, Zhou T, Xu JQ, Wang YX, Sun MM, He YJ, Pan SW, Xiong W, Peng ZK, Gao XH, Shang Y (January 2021). "Structure, kinetic properties and biological function of mechanosensitive Piezo channels". Cell & Bioscience. 11 (1): 13. doi:10.1186/s13578-020-00522-z. PMC 7796548. PMID 33422128.
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