Sulconazole

Sulconazole
Clinical data
Trade names	Exelderm
AHFS/Drugs.com	Monograph
MedlinePlus	a698018
Routes of; administration	Topical
ATC code	D01AC09 (WHO) ;
Identifiers
	IUPAC name 1-(2-{[(4-Chlorophenyl)methyl]sulfanyl}-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole;
CAS Number	61318-90-9 ;
PubChem CID	5318;
DrugBank	DB06820 ;
ChemSpider	5127 ;
UNII	5D9HAA5Q5S;
KEGG	D08535 ;
ChEBI	CHEBI:9325 ;
ChEMBL	ChEMBL1221 ;
CompTox Dashboard (EPA)	DTXSID8044129 ;
Chemical and physical data
Formula	C18H15Cl3N2S
Molar mass	397.74 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Clc1ccc(c(Cl)c1)C(SCc2ccc(Cl)cc2)Cn3ccnc3;
	InChI InChI=1S/C18H15Cl3N2S/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21/h1-9,12,18H,10-11H2 ; Key:AFNXATANNDIXLG-UHFFFAOYSA-N ;
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Sulconazole (trade name Exelderm) is an antifungal medication of the imidazole class. It is available as a cream or solution to treat skin infections such as athlete's foot, ringworm, jock itch, and tinea versicolor.^[1]^[2] Although not used commercially for insect control, sulconazole nitrate exhibits a strong anti-feeding effect on the keratin-digesting Australian carpet beetle larvae Anthrenocerus australis.^[3]

References

^ Drugs.com: sulconazole topical
^ Fromtling RA (April 1988). "Overview of medically important antifungal azole derivatives". Clinical Microbiology Reviews. 1 (2): 187–217. doi:10.1128/CMR.1.2.187. PMC 358042. PMID 3069196.
^ Sunderland MR, Cruickshank RH, Leighs SJ (2014). "The efficacy of antifungal azole and antiprotozoal compounds in protection of wool from keratin-digesting insect larvae". Textile Research Journal. 84 (9): 924–931. doi:10.1177/0040517513515312. S2CID 135799368.

[1] Drugs.com: sulconazole topical

[2] Fromtling RA (April 1988). "Overview of medically important antifungal azole derivatives". Clinical Microbiology Reviews. 1 (2): 187–217. doi:10.1128/CMR.1.2.187. PMC 358042. PMID 3069196.

[3] Sunderland MR, Cruickshank RH, Leighs SJ (2014). "The efficacy of antifungal azole and antiprotozoal compounds in protection of wool from keratin-digesting insect larvae". Textile Research Journal. 84 (9): 924–931. doi:10.1177/0040517513515312. S2CID 135799368.

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