Tombus virus defective interfering (DI) RNA region 3
| Tombus virus defective interfering (DI) RNA region 3 | |
|---|---|
 Predicted secondary structure and sequence conservation of Tombus_3_III | |
| Identifiers | |
| Symbol | Tombus_3_III |
| Rfam | RF00215 |
| Other data | |
| RNA type | Cis-reg |
| Domain(s) | Viruses |
| SO | SO:0000233 |
| PDB structures | PDBe |
Tombus virus defective interfering (DI) RNA region 3 is an important cis-regulatory region identified in the 3' UTR of Tombusvirus defective interfering particles (DI).[1]
Defective interfering RNAs are small sub-viral replicons which are non-coding deletion mutants of the virus that maintain cis-acting RNA elements necessary for replication of the host virus.[1] This conserved region of the 3'UTR has been found to enhance DI RNA accumulation by approximately 10-fold as well as mediating viral replication.[1]
See also
References
- ^ a b c Ray D, White KA (2003). "An internally located RNA hairpin enhances replication of Tomato bushy stunt virus RNAs". J. Virol. 77 (1): 245–257. doi:10.1128/JVI.77.1.245-257.2003. PMC 140596. PMID 12477830.