Trypanosome
Trypanosome may refer to:
- Trypanosomatida, a biological order within Kinetoplastida
 - Trypanosoma, a genus within Trypanosomatida whose members are often referred to as trypanosomes
 - Trypanosoma brucei, a major human pathogen that causes sleeping sickness
 - Trypanosoma cruzi, a major human pathogen that causes Chagas disease
 - A morphological class of trypanosomatid with a flagellum laterally attached to the cell body