2016 Karshi Challenger
| 2016 Karshi Challenger | |
|---|---|
| Date | 2–7 May |
| Edition | 10th |
| Draw | 32S / 16D |
| Prize money | $50,000+H |
| Surface | Hard |
| Location | Qarshi, Uzbekistan |
| Champions | |
| Singles | |
 Marko Tepavac | |
| Doubles | |
 Enrique López Pérez /  Jeevan Nedunchezhiyan | |
The 2016 Karshi Challenger was a professional tennis tournament played on hard courts. It was the tenth edition of the tournament which was part of the 2016 ATP Challenger Tour. It took place in Qarshi, Uzbekistan between 2 and 7 May 2016.
Singles main-draw entrants
Seeds
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 ISR | Dudi Sela | 78 | 1 |
 RUS | Karen Khachanov | 128 | 2 |
 MDA | Radu Albot | 151 | 3 |
 KAZ | Aleksandr Nedovyesov | 197 | 4 |
| ISR | Amir Weintraub | 198 | 5 |
 UKR | Denys Molchanov | 224 | 6 |
| KAZ | Dmitry Popko | 230 | 7 |
| RUS | Aslan Karatsev | 216 | 8 |
- 1 Rankings as of April 25, 2016.
Other entrants
The following players received wildcards into the singles main draw:
Pavel Tsoy- Sanjar Fayziev
- Temur Ismailov
- Shonigmatjon Shofayziyev
The following players received entry from the qualifying draw:
Sergey Betov- Denis Matsukevich
Francesco Vilardo- Richard Muzaev
The following player received entry as a lucky loser:
Champions
Singles
- Marko Tepavac def. Dudi Sela, 2–6, 6–3, 7–6(7–4)
Doubles
- Enrique López Pérez / Jeevan Nedunchezhiyan def.
Aleksandre Metreveli / Dmitry Popko, 6–1, 6–4