Androstenediol diacetate

Androstenediol diacetate
Clinical data
Other namesAndrostenediol 3,17-diacetate; 5-Androstenediol 3β,17β-diacetate; Androst-5-ene-3β,17β-diol 3β,17β-diacetate
Identifiers
  • [(3S,8R,9S,10R,13S,14S,17S)-17-Acetyloxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.016.604
Chemical and physical data
FormulaC23H34O4
Molar mass374.521 g·mol−1
3D model (JSmol)
  • CC(=O)O[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2C1)CC[C@@H]4OC(=O)C)C)C
  • InChI=1S/C23H34O4/c1-14(24)26-17-9-11-22(3)16(13-17)5-6-18-19-7-8-21(27-15(2)25)23(19,4)12-10-20(18)22/h5,17-21H,6-13H2,1-4H3/t17-,18-,19-,20-,21-,22-,23-/m0/s1
  • Key:QXKRUGDXPWHXHL-FQJIPJFPSA-N

Androstenediol diacetate, or 5-androstenediol 3β,17β-diacetate, also known as androst-5-ene-3β,17β-diol 3β,17β-diacetate, is a synthetic anabolic-androgenic steroid and an androgen ester – specifically, the C3β,17β diacetate diester of 5-androstenediol (androst-5-ene-3β,17β-diol) – which was never marketed.[1] The medication has been used with success to treat breast cancer in women.[2]

See also

References

  1. ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 86–. ISBN 978-1-4757-2085-3.
  2. ^ Dao TL (1975). "Pharmacology and Clinical Utility of Hormones in Hormone Related Neoplasms". In Sartorelli AC, Johns DG (eds.). Antineoplastic and Immunosuppressive Agents. Handbuch der experimentellen Pharmakologie / Handbook of Experimental Pharmacology. Springer. pp. 170–192. doi:10.1007/978-3-642-65806-8_11. ISBN 978-3-642-65806-8.
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