D-glutamate cyclase
| D-glutamate cyclase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.1.48 | ||||||||
| CAS no. | 37290-80-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme D-glutamate cyclase (EC 4.2.1.48) catalyzes the chemical reaction
- D-glutamate 5-oxo-Dproline + H2O
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is D-glutamate hydro-lyase (cyclizing; 5-oxo-D-proline-forming). This enzyme is also called D-glutamate hydro-lyase (cyclizing). This enzyme participates in D-glutamine and D-glutamate metabolism.
References
- MEISTER A, BUKENBERGER MW, STRASSBURGER M (1963). "The Optically-Specific Enzymatic Cyclization of D-Glutamate". Biochem. Z. 338: 217–29. PMID 14087295.