| Year | Nominee | Titles | Ref. |
| 1993 | Dave Dorman | Aliens: Tribes (Dark Horse Comics) | [1] |
| Simon Bisley | Lair of the Lizard Ladies in Mr. Monster Attacks #3 (Tundra Publishing) |
| John Bolton | Army of Darkness (Dark Horse Comics) |
| Dan Brereton | Clive Barker's Dread (Eclipse Comics) |
| Teddy Kristiansen | Tarzan: Loves, Lies, and the Lost City (Malibu Comics) |
| Dave McKean | Signal to Noise (VG Graphics/Dark Horse Comics) |
| Jim Woodring | Frank in the River (Tundra Publishing), "Frank" in Pictopia #2 (Fantagraphics Books) |
| 1994 | Alex Ross | Marvels (Marvel Comics) | [2] |
| Mark Chiarello | Batman/Houdini: The Devil's Workshop (DC Comics) |
| Scott Hampton | The Upturned Stone (Kitchen Sink Press) |
| Teddy Kristiansen | Grendel Tales: Four Devils, One Hell (Dark Horse Comics) |
| 1995 | Jon J. Muth | The Mystery Play (DC Comics/Vertigo Comics) | [3] |
| Christopher Moeller | Shadow Empires: Faith Conquers (Dark Horse Comics) |
| Miguelanxo Prado | Streak of Chalk (NBM Publishing) |
| Jim Silke | Rascals in Paradise (Dark Horse Comics) |
| Jim Woodring | Jim (Fantagraphics Books) |
| 1996 | John Bolton | Batman: Manbat (DC Comics/Vertigo Comics) | [4] |
| Dan Brereton | The Nocturnals (Malibu Comics/Bravura Comics) |
| Teddy Kristiansen | Bacchus Color Special (Dark Horse Comics) |
| David Wenzel | Fairy Tales of the Brothers Grimm (NBM Publishing) |
| Phil Winslade | Goddess (DC Comics/Vertigo Comics) |
| 1997 | Alex Ross | Kingdom Come (DC Comics) | [5] |
| Dan Brereton | Batman: Thrillkiller (DC Comics) |
| Joseph Michael Linsner | Dawn (Sirius Entertainment) |
| Miguelanxo Prado | Tangents (NBM Publishing) |
| 1998 | Alex Ross | Uncle Sam (DC Comics/Vertigo Comics) | [6] |
| John Bolton | Menz Insana (DC Comics/Vertigo Comics), "The Flowers of Romance" in Vertigo: Winter's Edge (DC Comics/Vertigo Comics) |
| Gene Ha | "Free Fall" in Shadows & Light (Marvel Comics) |
| Scott Hampton | Batman: Dark Knight Dynasty (DC Comics), Destiny: A Chronicle of Deaths Foretold Book Two (DC Comics/Vertigo Comics) |
| David Wenzel | The Wizard's Tale (Homage Comics) |
| 1999 | Alex Ross | Superman: Peace on Earth (DC Comics) | [7] |
| Kyle Baker | You Are Here (DC Comics/Vertigo Comics) |
| Dan Brereton | Batgirl and Batman: Thrillkiller '62 (DC Comics) |
| David W. Mack | Kabuki (Image Comics) |
| 2000s |
| 2000 | Alex Ross | Batman: War on Crime (DC Comics) | [8] |
| Kyle Baker | I Die at Midnight (DC Comics/Vertigo Comics), "Letitia Lerner, Superman's Babysitter" in Elseworlds 80-Page Giant (DC Comics) |
| John Bolton | Gifts of the Night (DC Comics/Vertigo Comics) |
| Jill Thompson | Scary Godmother: The Mystery Date (Sirius Entertainment) |
| 2001 | Jill Thompson | Scary Godmother (Sirius Entertainment) | [9] |
| Christian Gossett and Team Red Star | The Red Star (Image Comics) |
| David W. Mack | Kabuki #9 (Image Comics) |
| George Pratt | Batman: Harvest Breed (DC Comics) |
| Charles Vess | Rose #1 (Cartoon Books) |
| Yslaire | From Cloud 99: Memories, Part 1 (Humanoids Publishing) |
| 2002 | Charles Vess | Rose (Cartoon Books) | [10] |
| Allen Coulter and Snakebite Cortez | The Red Star (Image Comics) |
| Dave McKean | Pictures That Tick (Hourglass Studios/Allen Spiegel Fine Arts) |
| David W. Mack | Daredevil #16-19 (Marvel Comics) |
| John Van Fleet | Batman: The Ankh (DC Comics) |
| 2003 | George Pratt | Wolverine: Netsuke (Marvel Comics) | [11] |
| Eric Drooker | Blood Song: A Silent Ballad (Harcourt) |
| David W. Mack | Kabuki: The Ghost Play (Image Comics) |
| Lorenzo Mattotti | Dr. Jekyll & Mr. Hyde (NBM Publishing) |
| 2004 | Jill Thompson | "Stray" in The Dark Horse Book of Hauntings (Dark Horse Comics) | [12] |
| Juanjo Guarnido | Blacksad (ibooks) |
| Ladronn | Hip Flask: Elephantmen (Comicraft) |
| Miguelanxo Prado | "Dream" in The Sandman: Endless Nights (Vertigo Comics/DC Comics) |
| Frank Quitely | "Destiny" in The Sandman: Endless Nights (Vertigo Comics/DC Comics) |
| 2005 | Teddy Kristiansen | It's a Bird... (Vertigo Comics/DC Comics) | [13] |
| Juanjo Guarnido | Blacksad, Book 2: Arctic Nation (ibooks) |
| David W. Mack | Kabuki (Marvel Comics) |
| Ben Templesmith | 30 Days of Night: Return to Barrow (IDW Publishing) |
| Michael Zulli | Creatures of the Night (Dark Horse Comics) |
| 2006 | Ladronn | Hip Flask: Mystery City (Active Images) | [14] |
| Paul Guinan | Heartbreakers Meet Boilerplate (IDW Publishing) |
| Ben Templesmith | Fell (Image Comics) |
| Kent Williams | The Fountain (Vertigo Comics/DC Comics) |
| 2007 | Jill Thompson | "A Dog and His Boy" in The Dark Horse Book of Monsters (Dark Horse Comics), "Love Triangle" in Sexy Chix (Dark Horse Comics), "Fair Division" in Fables: 1001 Nights of Snowfall (Vertigo Comics/DC Comics) | [15] |
| Nicolas de Crécy | Glacial Period (NBM Publishing) |
| Melinda Gebbie | Lost Girls (Top Shelf Productions) |
| Ben Templesmith | Fell (Image Comics), The Looking Glass Wars: Hatter M (Desperado Publishing/Image Comics), Wormwood: Gentleman Corpse (IDW Publishing) |
| Brett Weldele | Southland Tales: The Prequel Saga (Graphitti Designs), Silent Ghost (Markosia) |
| 2008 | Eric Powell | The Goon: Chinatown (Dark Horse Comics) | [16] |
| Ann Marie Fleming | The Magical Life of Long Tack Sam (Riverhead Books/Penguin Group) |
| Bryan Talbot | Alice in Sunderland (Dark Horse Comics) |
| Ben Templesmith | Fell (Image Comics), 30 Days of Night: Red Snow (IDW Publishing), Wormwood: Gentleman Corpse (IDW Publishing) |
| 2009 | Jill Thompson | Magic Trixie (Harper Children's Books), Magic Trixie Sleeps Over (Harper Children's Books) | [17][18] |
| Lynda Barry | What It Is (Drawn & Quarterly) |
| Eddie Campbell | The Amazing Remarkable Monsieur Leotard (First Second Books) |
| Enrico Casarosa | The Venice Chronicles (Ateliér Fio/AdHouse Books) |
| Scott Morse | Tiger!Tiger!Tiger! (Red Window) |
| 2010s |
| 2010 | Jill Thompson | Beasts of Burden (Dark Horse Comics), Magic Trixie and the Dragon (Harper Children's Books) | [19][20] |
| Émile Bravo | My mommy is in America and she met Buffalo Bill (Fanfare/Ponent Mon) |
| Mauro Cascioli | Justice League: Cry for Justice (DC Comics) |
| Nicolle Rager Fuller | Charles Darwin on the Origin of Species: A Graphic Adaptation (Rodale Books) |
| Carol Tyler | You’ll Never Know: A Good and Decent Man (Fantagraphics Books) |
| 2011 | Juanjo Guarnido | Blacksad (Dark Horse Comics) | [21][22] |
| Lynda Barry | Picture This: The Nearsighted Monkey Book (Drawn & Quarterly) |
| Brecht Evens | The Wrong Place (Drawn & Quarterly) |
| Janet K. Lee | Return of the Dapper Men (Archaia Entertainment) |
| Éric Liberge | On the Odd Hours (NBM Publishing) |
| Carol Tyler | You’ll Never Know Book 2: Collateral Damage (Fantagraphics Books) |
| 2012 | There was no Eisner Award for Best Painter/Multimedia Artist in 2012 as the judges "didn't find enough contenders that reached the level of quality they were looking for."[23] |
| 2013 | Juanjo Guarnido | Blacksad (Dark Horse Comics) | [24][22] |
| Brecht Evens | The Making Of (Drawn & Quarterly) |
| Teddy Kristiansen | The Red Diary/The RE[a]D Diary (Man of Action Entertainment/Image Comics) |
| Lorenzo Mattotti | The Crackle of the Frost (Fantagraphics Books) |
| Katsuya Terada | The Monkey King, vol. 2 (Dark Horse Comics) |
| 2014 | Fiona Staples | Saga (Image Comics) | [25][22] |
| Andrew C. Robinson | The Fifth Beetle (Dark Horse Comics) |
| Sonia Sanchéz | Here I Am (Capstone Publishers) |
| Ive Svorcina | Thor (Marvel Comics) |
| Marguerite Van Cook | 7 Miles a Second (Fantagraphics Books) |
| Judith Vanistendael | When David Lost His Voice (SelfMadeHero) |
| 2015 | J. H. Williams III | The Sandman: Overture (Vertigo Comics/DC Comics) | [26][22] |
| Lauri Ahonen and Jaakko Ahonen | Jaybird (Dark Horse Comics) |
| Colleen Coover | Bandette (MonkeyBrain Books) |
| Mike del Mundo | Elektra (Marvel Comics) |
| Juanjo Guarnido | Blacksad: Amarillo (Dark Horse Comics) |
| 2016 | Dustin Nguyen | Descender (Image Comics) | [27][22] |
| Federico Bertolucci | Love: The Tiger (Magnetic Press), Love: The Fox (Magnetic Press) |
| Colleen Coover | Bandette (MonkeyBrain Books) |
| Carita Lupattelli | Izuna (Humanoids Publishing) |
| Tony Sandoval | A Glance Backward (Magnetic Press) |
| 2017 | Jill Thompson | Wonder Woman: The True Amazon (DC Comics), Beasts of Burden: What the Cat Dragged In (Dark Horse Comics) | [28][22] |
| Federico Bertolucci | Love: The Lion (Magnetic Press) |
| Brecht Evens | Panther (Drawn & Quarterly) |
| Manuele Fior | 5,000 km per Second (Fantagraphics Books) |
| Dave McKean | Black Dog: the Dreams of Paul Nash (Dark Horse Comics) |
| Sana Takeda | Monstress (Image Comics) |
| 2018 | Sana Takeda | Monstress (Image Comics) | [29][22] |
| Federico Bertolucci | Love: The Dinosaur (Lion Forge Comics/Magnetic Press), Little Tails (Lion Forge Comics/Magnetic Press) |
| EFA | Monet: Itinerant of Light (NBM Publishing) |
| Jean-Pierre Gibrat | Flight of the Raven (EuroComics/IDW Publishing) |
| Cyril Pedrosa | Portugal (NBM Publishing) |
| 2019 | Dustin Nguyen | Descender (Image Comics) | [30][31] |
| Lee Bermejo | Batman: Damned (DC Comics) |
| Carita Lupatelli | Izuna, book 2 (Humanoids Publishing) |
| Grégory Panaccione | A Sea of Love (Magnetic Press/Lion Forge Comics) |
| Tony Sandoval | Watersnakes (Magnetic Press/Lion Forge Comics) |
| 2020s |
| 2020 | Christian Ward | Invisible Kingdom (Berger Books/Dark Horse Comics) | [32][33] |
| Didier Cassegrain | Black Water Lilies (Europe Comics) |
| Alexandre Clérisse | Diabolical Summer (IDW Publishing) |
| David W. Mack | Cover (DC Comics) |
| Léa Mazé | Elma, A Bear’s Life, vol. 1: The Great Journey (Europe Comics) |
| Julie Rocheleau | Wrath of Fantômas (Titan Books) |
| 2021 | Anand RK/John Pearson | Blue in Green (Image Comics) | [34][35] |
| Benjamin Adam | Soon (Europe Comics) |
| Alice Chemama | The Zolas (Europe Comics) |
| Jared Cullum | Kodi (Top Shelf Productions) |
| Decur | When You Look Up (Enchanted Lion Books) |
| Antonio Lapone | Gentlemind (Europe Comics) |
| 2022 | Sana Takeda | Monstress (Image Comics) | [36] |
| Federico Bertolucci | Brindille, Love: The Mastiff (Magnetic) |
| John Bolton | Hell’s Flaw (Renegade Arts Entertainment) |
| Juan Cavia | Ballad for Sophie (Top Shelf) |
| Frank Pe | Little Nemo (Magnetic) |
| Ileana Surducan | The Lost Sunday (Pronoia AB) |