Glucametacin
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| Clinical data | |
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| Trade names | Teoremac |
| Other names | Indometacin glucosamide |
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| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.052.640 |
| Chemical and physical data | |
| Formula | C25H27ClN2O8 |
| Molar mass | 518.95 g·mol−1 |
Glucametacin is a non-steroidal anti-inflammatory drug used for the treatment of mild or moderate pain associated with rheumatoid arthritis, osteoarthritis, and other rheumatological disorders.[1] It has analgesic and anti-inflammatory effects.[1][2][3]
Glucametacin is an amide of indometacin with glucosamine.
References
- ^ a b Capelli L, Chianese V, La Montagna G, Giordano M (1981). "Further studies on glucametacin in rheumatoid arthritis and in other chronic types of rheumatism". Current Medical Research and Opinion. 7 (4): 227–233. doi:10.1185/03007998109114267. PMID 6971729.
- ^ Akatsu T, Catanzaro Guimarães SA (1986). "Comparative effects of non-steroidal anti-inflammatory drugs, mefenamic acid, metiazinic acid and glucametacin on the inflammatory response induced by subcutaneous implantation of human dental plaque and on the mitotic activity of isoproterenol-stimulated parotid glands of rats". Cellular and Molecular Biology. 32 (5): 619–626. PMID 3779763.
- ^ Ibba G, Uras R, Perpignano G (1983). "Double-blind comparison of glucametacin and ketoprofen in chronic arthropathies". Current Medical Research and Opinion. 8 (5): 321–326. doi:10.1185/03007998309112391. PMID 6340973.