 |
| HLA-B (alpha)-β2MG with bound peptide |
major histocompatibility complex (human), class I, B63 |
| Alleles | *1516, *1517 |
| Structure (See HLA-B) |
| Shared data |
| Locus | chr.6 6p21.31 |
HLA-B63 (B63) is an HLA-B serotype. The serotype identifies certain B*15 gene-allele protein products of HLA-B.[1]
B63 is one of many split antigens of the broad antigen, B15. B63 identifies the B*1516 and B*1517 allele products.
Serotype
Serotypes B15, B62, B63, B70, B71, B72, B75, B76, B77 recognition of the
HLA B*15 gene products[2] | B*15 | B15 | B62 | B63 | B70 | B71 | B72 | B75 | B76 | B77 | Sample |
| allele | % | % | % | % | % | % | % | % | % | size (N) |
| *1516 | 3 | | 80 | | | | | | | 816 |
| *1517 | 2 | | 88 | | | | | | | 797 |
| Alleles link-out to IMGT/HLA Databease at EBI |
Alleles
HLA B*1516 frequencies | | freq |
| ref. | Population | (%) |
| [3] | Ivory Coast Akan Adiopodoume | 4.6 |
| Cameroon Bamileke | 3.2 |
| USA African Americans (3) | 1.9 |
| Italy South Campania | 1.6 |
| United Arab Emerates | 1.5 |
| Brazil | 1.4 |
| Azores S. Maria and S. Miguel | 1.3 |
| Zimbabwe Harare Shona | 1.3 |
| Cameroon Beti | 1.1 |
| Cameroon Yaounde | 1.1 |
| Mali Bandiagara | 1.1 |
| Tunisia Tunis | 1.1 |
| Kenya Nandi | 1.0 |
| Cape Verde SE Islands | 0.8 |
| Kenya | 0.7 |
| Uganda Kampala | 0.6 |
| Brazil Belo Horizonte | 0.5 |
| South African Natal Zulu | 0.5 |
| Sudanese | 0.5 |
| Tunisia | 0.5 |
| Kenya Luo | 0.4 |
| Oman | 0.4 |
HLA B*1517 frequencies | | freq |
| ref. | Population | (%) |
| [3] | India Khandesh Pawra | 9.0 |
| South Africa Natal Tamil | 3.1 |
| Saudi Arabia Guraiat and Hail | 2.7 |
| Mexico Zaptotec Oaxaca | 2.2 |
| India North Hindus | 1.9 |
| Bulgaria | 1.8 |
| India North Delhi | 1.6 |
| China Inner Mongolia | 1.5 |
| Georgia Tbilisi Georgians | 1.4 |
| Kenya Luo | 1.3 |
| Cuban Mulatto | 1.2 |
| Brazil Belo Horizonte | 1.1 |
| Cameroon Yaounde | 1.1 |
| Portugal North | 1.1 |
| Tunisia Tunis | 1.1 |
| Kenya Nandi | 1.0 |
| Portugal Centre | 1.0 |
| China Qinghai Hui | 0.9 |
| Israel Ashk. and Non Ashk.i Jews | 0.9 |
| Azores Terceira Island | 0.8 |
| Cape Verde Southeastern Islands | 0.8 |
| France South East | 0.8 |
| India New Delhi | 0.8 |
| Russia Tuva pop 2 | 0.8 |
| Sudanese | 0.8 |
| USA African Americans pop3 | 0.8 |
| USA Caucasian pop2 | 0.8 |
| Brazil | 0.7 |
| Cuban White | 0.7 |
| Thailand | 0.7 |
| USA Philadelphia Caucasians | 0.7 |
| Cameroon Beti | 0.6 |
| Romanian | 0.6 |
| Czech Republic | 0.5 |
| Singapore Thai | 0.5 |
| Spain Eastern Andalusia Gipsy | 0.5 |
References
- ^ Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
- ^ derived from IMGT/HLA
- ^ a b Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database". Tissue Antigens. 61 (5): 403–407. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.