Kisii
Kisii may refer to:
- Kisii, Kenya, a municipality and the capital of Kisii County
 - Kisii County, one of the 47 counties of Kenya
 - Kisii District, a former district of Kenya
 - Gucha District, in Kenya, also known as South Kisii District
 - Nyamira District, in Kenya, also known as North Kisii District
 - Kisii people, an ethnic group in Kenya, also known as Abagusii or Gusii people
 - Gusii language, Bantu language spoken by the Kisii people
 - Kisii School for the Deaf, the only Deaf-run school for Deaf children in Kenya
 - Kisii stone, a name for soapstone, quarried in Tabaka area of southern Kisii District
 - Kisii University, Kenya