| Name | Original chapter | Notability | References |
| Buster Barnett | Lambda Eta (Arkansas State University) | NFL player, (Buffalo Bills) | [49] |
| Fred Barnett | Lambda Eta (Arkansas State University) | NFL player (Philadelphia Eagles, Miami Dolphins) | [49] |
| Idrees Bashir | Delta Nu (University of Memphis) | NFL player (Indianapolis Colts, Carolina Panthers, Detroit Lions) | [49] |
| Charlie Batch | Zeta Epsilon (Eastern Michigan University) | NFL player with the Detroit Lions and Pittsburgh Steelers; Super Bowl XL | [49][50] |
| Larry Brown | Zeta Nu (University of Georgia) | NFL player | [49][51] |
| Lomas Brown | Zeta Kappa (University of Florida) | NFL player (5 teams), 7 time All-Pro selection, 7 time Pro Bowl selection; Super Bowl XXXVII champion | [49][50] |
| Kenny O. Burrough | Beta Delta (Texas Southern University) | NFL player with the New Orleans Saints and Houston Oilers | [49] |
| Ernie Calloway | Beta Delta (Texas Southern University) | NFL player | [49] |
| Rich Caster | Alpha Beta (Jackson State University) | NFL player, Pro Bowl in 1972, 1974, 1975 (New York Jets, Houston Oilers, New Orleans Saints, Washington Redskins) | [49] |
| Jamar Chaney | Theta Iota (Mississippi State University) | NFL player (Philadelphia Eagles) | [49] |
| Ben Coates | Upsilon (Livingstone College) | NFL player with the New England Patriots and Baltimore Ravens; Super Bowl XXXV champion | [49][6] |
| Johnie Cooks | Theta Iota (Mississippi State University) | NFL player with the Indianapolis Colts, New York Giants, and the Cleveland Browns | [49] |
| DeMarcus Curry | Kappa Zeta (Auburn University) | NFL player with the Tampa Bay Buccaneers | [49] |
| Eric Curry | Theta Delta (University of Alabama) | NFL player (Tampa Bay Buccaneers, Jacksonville Jaguars), played on the 1992 National Champion Alabama Crimson Tide team | [49][52][6] |
| Lional Dalton | Zeta Epsilon (Eastern Michigan University) | NFL player (5 teams),Super Bowl XXXV champion | [49] |
| Phillip Daniels | Zeta Nu (University of Georgia) | NFL player with the Seattle Seahawks, Chicago Bears, and Washington Redskins | [49][51] |
| Willie Davis | Iota Pi (University of Central Arkansas) | NFL player with the Kansas City Chiefs and Houston Oilers | [49][6] |
| Hugh Douglas | Nu Sigma (Philadelphia) | NFL player with the New York Jets, Philadelphia Eagles, and Jacksonville Jaguars; 3 Time Pro Bowl selection(2000,2001,2002); and 1995 NFL Defensive Rookie of the Year | [49] |
| Marques Douglas | Alpha (Howard University) | NFL player with the New York Jets | [49] |
| Braylon Edwards | Gamma Alpha Sigma (Cleveland, Ohio) | NFL player with the New York Jets, All-Pro selection (2007), Pro Bowl selection (2007), Fred Biletnikoff Award winner (2004) | [49][53] |
| Robert Edwards | Zeta Nu (University of Georgia) | NFL player with the New England Patriots and Miami Dolphins; CFL player | [49][51] |
| Terrence Edwards | Zeta Nu (University of Georgia) | NFL player with the Atlanta Falcons and CFL player | [51] |
| Donnie Elder | Delta Nu (University of Memphis) | NFL player (5 teams) | [49] |
| Charlie Strong | Iota Pi (University of Central Arkansas) | Head football coach at the University of South Florida[54] | [49] |
| Harry Galbreath | Kappa Chi (University of Tennessee) | NFL player with the Miami Dolphins, Green Bay Packers, and the New York Jets | [49] |
| Tony Gilbert | Zeta Nu (University of Georgia) | NFL player with the Arizona Cardinals, Jacksonville Jaguars, and Atlanta Falcons | [55] |
| Victor Green | Iota Beta (University of Akron) | NFL player with the New York Jets, New England Patriots, and New Orleans Saints | [49] |
| L. C. Greenwood | Beta Theta (University of AR-Pine Bluff) | NFL player with the Pittsburgh Steelers; Super Bowl IX, Super Bowl X, Super Bowl XIII, and Super Bowl XIV champion | [49][6] |
| Dudley Guice, Jr. | Zeta Iota (Northwestern State University of Louisiana) | NFL player with the Tennessee Titans | [56] |
| Myron Guyton | Iota Delta (Eastern Kentucky University) | NFL player with the New York Giants and New England Patriots; (Super Bowl XXV) champion | [49] |
| Chris Harris | Beta Rho Sigma (Charlotte, North Carolina) | NFL player with the Chicago Bears and Carolina Panthers | [49] |
| Corey Alan Harris | Beta Beta Alpha (University of North Alabama) | NFL player with the New Orleans Saints and Kansas City Chiefs | [57] |
| Chris Hayes | Alpha Beta Alpha (Washington State University) | NFL player with the Green Bay Packers, New York Jets, and New England Patriots; Super Bowl XXXI champion | [49] |
| Verron Haynes | Zeta Nu (University of Georgia) | NFL player with the Atlanta Falcons and Pittsburgh Steelers; 2-time Super Bowl Champion | [51] |
| Claude Humphrey | Zeta Alpha (Tennessee State University) | Pro Football Hall of Fame inductee; NFL player with the Atlanta Falcons and Philadelphia Eagles; 1968 NFL Defensive Rookie of the Year, | [49] |
| Donald Igwebuike | Omicron Lambda (Clemson University) | NFL player with the Tampa Bay Buccaneers and the Minnesota Vikings | [49] |
| Ken Irvin | Delta Nu (University of Memphis) | NFL player with the Buffalo Bills, New Orleans Saints, and Minnesota Vikings | [49] |
| Darrius Johnson | Xi Delta (University of Oklahoma) | NFL player with the Denver Broncos and Kansas City Chiefs; Super Bowl XXXII and Super Bowl XXXIII champion | [49] |
| Aaron Jones | Iota Delta (Eastern Kentucky University) | NFL player with the Pittsburgh Steelers, New England Patriots, and Miami Dolphins | [49] |
| Mike London | Mu Omicron | Head coach of the Howard Bison football team | [58] |
| Ray McDonald | Zeta Kappa (University of Florida) | NFL player with the San Francisco 49ers; played on 2006 National Champion 2006 Florida Gators Football team | [50] |
| Willis McGahee | Zeta Iota Sigma (Delray Beach, Florida) | NFL player with the Buffalo Bills and Baltimore Ravens; played on championship 2001 Miami Hurricanes football team | [49] |
| Ben McGee | Alpha Beta (Jackson State University) | NFL player with the Pittsburgh Steelers, 2-time Pro Bowl selection | [49] |
| Brandon Miller | Zeta Nu (University of Georgia) | NFL player with the Atlanta Falcons and Seattle Seahawks | [49][51] |
| Marques Douglas | Alpha (Howard University) | NFL player Bwith the Baltimore Ravens | [49] |
| Nate Miller | Iota Tau (Louisiana State University) | NFL player with the Atlanta Falcons | [49] |
| Michael Moore | Theta Delta (University of Alabama) | NFL player with the Washington Redskins and Atlanta Falcons | [59] |
| Lloyd Mumphord | Beta Delta (Texas Southern University) | NFL player | [49] |
| Nate Newton | | NFL player with the Dallas Cowboys and Carolina Panthers | [49] |
| Christopher Owens | Mu Lambda (San Jose State University) | NFL player with the Atlanta Falcons | [60] |
| Jeff Owens | Zeta Nu (University of Georgia) | NFL player with the Philadelphia Eagles | [49] |
| Bubba Paris | Delta Rho (University of Michigan) | NFL player with the San Francisco 49ers, Indianapolis Colts, and Detroit Lions; Super Bowl XIX, Super Bowl XXIII, and Super Bowl XXIV champion | [49] |
| Jaret Patterson | Zeta Chi Sigma (Prince George's County, MD & Metropolitan DC) | NFL player with the Washington Commanders | [49] |
| Marvcus Patton | Nu Delta (UC Los Angeles) | NFL player with the Buffalo Bills, Washington Redskins, and the Kansas City Chiefs | [49] |
| Eddie Payton | Alpha Beta (Jackson State University) | NFL player (4 teams), head golf coach at Jackson State University | [49] |
| Todd Pinkston | Theta Eta (University of S. Mississippi) | NFL player with the Philadelphia Eagles | [49] |
| Joey Porter | Nu Xi (Colorado State University) | NFL player with the Pittsburgh Steelers and the Miami Dolphins; Super Bowl XL champion | [49][6] |
| Travis Prentice | Omicron Xi (Murray State University) | NFL player with the Cleveland Browns, Minnesota Vikings, and Arizona Cardinals | [49] |
| Jerry Rice | Delta Phi (Mississippi Valley State University) | NFL player with the San Francisco 49ers and 3 others); Pro Football Hall of Fame Class of 2010, College Football Hall of Fame; Super Bowl XXIII, Super Bowl XXIV, and Super Bowl XXIX) champion; 2005 Dancing with the Stars Runner-Up | [49][6] |
| Dominique Rodgers-Cromartie | Eta Beta Sigma (Nashville, Tennessee) | NFL player with Arizona Cardinals | [61] |
| Adrian Ross | Nu Xi (Colorado State University) | NFL player with the Cincinnati Bengals | [49] |
| Dwayne Rudd | Theta Delta (University of Alabama) | NFL player with the Minnesota Vikings, Cleveland Browns, and the Tampa Bay Buccaneers | [62] |
| George Selvie | Zeta Xi (University of South Florida) | NFL player with the Dallas Cowboys | [63] |
| Terrance Shaw | Epsilon Upsilon (Stephen F. Austin State University) | NFL player (5 teams) and Super Bowl XXXVI champion | [49] |
| Richard Sherman | Beta Tau (Stanford Uni.) | NFL player with the Seattle Seahawks and Super Bowl XLVIII champion | [64] |
| DJ Shockley | Zeta Nu (University of Georgia) | NFL player with the Atlanta Falcons, 2005 SEC Championship Game MVP | [55] |
| Ron Simpkins | Delta Rho (University of Michigan) | NFL player with the Cincinnati Bengals and Green Bay Packers | [49] |
| Ryan Sims | Xi Gamma (University of North Carolina) | NFL player with the Kansas City Chiefs and Tampa Bay Buccaneers | [49] |
| Jackie Slater | Alpha Beta (Jackson State University) | NFL player with the Los Angeles Rams and the St. Louis Rams, Pro Football Hall of Fame | [49] |
| Jessie Small | Nu Sigma (Philadelphia) | NFL with the ePhiladelphia Eagles and CFL player | [49] |
| Emmitt Smith | Zeta Kappa (University of Florida) | NFL player with the Dallas Cowboys and Arizona Cardinals; Pro Football Hall of Fame; Super Bowl XXVII, Super Bowl XXVIII, and Super Bowl XXX) champion; 2006 Dancing with the Stars champion | [49][50][6] |
| John Stephens | Zeta Iota (Northwestern State University) | NFL player (four teams); Pro Bowler; 1988 NFL Offensive Rookie of the Year | [49][6] |
| James Starks | Beta Iota (University at Buffalo) | NFL player with the Green Bay Packers | [65] |
| Marcus Stroud | Zeta Nu (University of Georgia) | NFL player with the Jacksonville Jaguars and Buffalo Bills | [51] |
| Darrell Stuckey | Zeta Omicron (University of Kansas) | NFL player with the San Diego Chargers | [49] |
| Chris Terry | Zeta Nu (University of Georgia) | NFL player with the Carolina Panthers, Seattle Seahawks, and Kansas City Chiefs | [49][51] |
| Kiwaukee Thomas | Pi Rho (Georgia Southern University) | NFL player (four teams) | [49] |
| Marcus Thomas | Zeta Kappa (University of Florida) | NFL player with the Denver Broncos, played on the 2006 National Champion Florida Gators team | [50] |
| Ricky Thomas | Theta Delta (University of Alabama) | assistant coach of the Indianapolis Colts | [49] |
| George Thornton | Theta Delta (University of Alabama) | NFL player with the San Diego Chargers and New York Giants | [49][66] |
| Elijah Thurmon | Alpha (Howard University) | NFL player | [49] |
| Lewis Tillman | Alpha Beta (Jackson State University) | NFL player with the New York Giants and Chicago Bears, Super Bowl XXV champion | [49] |
| Willie Totten | Delta Phi (Mississippi Valley State University) | NFL player with the Buffalo Bills, member of College Football Hall of Fame (as part of the Satellite Express (with Jerry Rice) which set many NCAA offensive records) | [49] |
| Deshea Townsend | Theta Delta (University of Alabama) | NFL player with the Pittsburgh Steelers; Super Bowl XL and Super Bowl XLIII champion | [6] |
| Tony Vinson | Theta Omicron (Towson University) | NFL player with the Baltimore Ravens | [49] |
| Hines Ward | Zeta Nu (University of Georgia) | NFL player with the Pittsburgh Steelers; Super Bowl XL and Super Bowl XLIII champion | [49][51][6] |
| James Washington | Kappa Delta Sigma (Los Angeles) | NFL player with the Los Angeles Rams, Dallas Cowboys, and Washington Redskins; Super Bowl XXVII and Super Bowl XXVIII champion | [49][6] |
| Tracy White | Alpha (Howard University) | NFL player (4 teams) | [49] |
| Willie Whitehead | Kappa Zeta (Auburn University) | NFL player with the San Francisco 49ers and the New Orleans Saints]] | [49][67] |
| Wilson Whitley | Zeta Zeta (University of Houston) | NFL player | [49] |
| Erik Williams | Nu (Central State University) | NFL player with the Dallas Cowboys; Super Bowl XXVII, Super Bowl XXVIII, and Super Bowl XXX champion | [49][6] |
| Willie Williams | Pi Mu (Western Carolina) | NFL player with the Pittsburgh Steelers and Seattle Seahawks Super Bowl XL champion | [49] |
| Todd Williams | Mu Epsilon (Florida State University) | NFL, AFL, and UFL player | [49] |
| Craig Yeast | Mu Theta (University of Kentucky) | NFL player with the Cincinnati Bengals and the New York Jets | [49] |