| Appointed/accreditation  |  Incumbent  |  Monarch  |  Envoy to  |  Left office  | 
  | 1505  |  John Stile[3]  |  Henry VIII of England  |  Ferdinand II of Aragon  |  16 June 1518  | 
  | 3 June 1512  |  William Knight[4]  |  Henry VIII of England  |  Ferdinand II of Aragon  |  1 September 1513  | 
  | 15 July 1517  |  Sir Thomas Spinelly[5]  |  Henry VIII of England  |  Charles I of Spain  |  1522  | 
  | 28 February 1518  |  John Kite[6] John Bourchier, 2nd Baron Berners[7]  |  Henry VIII of England  |  Charles I of Spain  |  1 March 1519  | 
  | 1533  |  Richard Pate  |  Henry VIII of England  |  Charles I of Spain  |  1537  | 
  | 1537  |  Sir Thomas Wyatt[8]  |  Henry VIII of England  |  Charles I of Spain  |  1539  | 
  | 12 March 1554  |  John Russell, 1st Earl of Bedford Thomas Radclyffe, 3rd Earl of Sussex  |  Mary I of England  |  Philip II of Spain  |  20 July 1554  | 
  | 12 January 1560  |  Anthony Browne, 1st Viscount Montagu  |  Elizabeth I of England  |  Philip II of Spain  |  24 June 1560  | 
  | 24 June 1560  |  Anthony Browne, 1st Viscount Montagu Sir Thomas Chamberlain[9]  |  Elizabeth I of England  |  Philip II of Spain  |  24 June 1562  | 
  | 30 September 1561  |  Thomas Chaloner  |  Elizabeth I of England  |  Philip II of Spain  |  15 May 1565  | 
  | 5 March 1565  |  William Phayre  |  Elizabeth I of England  |  Philip II of Spain  |  4 April 1566  | 
  | 12 January 1566  |  John Man[10]  |  Elizabeth I of England  |  Philip II of Spain  |  5 October 1568  | 
  | 18 November 1576  |  Sir John Smith[11][12]  |  Elizabeth I of England  |  Philip II of Spain  |  28 July 1577  | 
  | December 1577  |  Thomas Wilkes[13]  |  Elizabeth I of England  |  Philip II of Spain  |  February 1578  | 
  | May 1579  |  Edward Wotton, 1st Baron Wotton  |  Elizabeth I of England  |  Philip II of Spain  |    | 
  | January 1583  |  William Wade  |  Elizabeth I of England  |  Philip II of Spain  |  August 1584  | 
  | 1584  |  Thomas Wilson  |  Elizabeth I of England  |  Philip II of Spain  |    | 
  | 2 March 1605  |  Charles Howard, 1st Earl of Nottingham  |  James VI and I  |  Philip III of Spain  |  4 July 1577  | 
  | 1605  |  Francis Cottington, 1st Baron Cottington  |  James VI and I  |  Philip III of Spain  |    | 
  | 1605  |  Charles Cornwallis[14]  |  James VI and I  |  Philip III of Spain  |  1609  | 
  | 1608  |  John Digby, 1st Earl of Bristol  |  James VI and I  |  Philip III of Spain  |    | 
  | 1609  |  Francis Cottington, 1st Baron Cottington[15]  |  James VI and I  |  Philip III of Spain  |  1611  | 
  | 1609  |  Peter Wyche  |  James VI and I  |  Philip IV of Spain  |  1611  | 
  | 1616  |  William Cecil, 17th Baron de Ros  |  James VI and I  |  Philip III of Spain  |    | 
  | 1617  |  John Digby, 1st Earl of Bristol[16]  |  James VI and I  |  Philip IV of Spain  |  1618  | 
  | 1617  |  John Digby, 1st Earl of Bristol  |  James VI and I  |  Philip III of Spain  |    | 
  | 1618  |  Walter Aston, 1st Lord Aston of Forfar  |  James VI and I  |  Philip III of Spain  |    | 
  | 1622  |  Mr. Hole  |  James VI and I  |  Philip IV of Spain  |    | 
  | 1622  |  Simon Digby (fl. 1620–1640s)  |  James VI and I  |  Philip IV of Spain  |  1640  | 
  | 1622  |  John Digby, 1st Earl of Bristol  |  James VI and I  |  Philip IV of Spain  |    | 
  | 1623  |  Endymion Porter  |  James VI and I  |  Philip IV of Spain  |    | 
  | 1624  |  Stephen Gardiner  |  James VI and I  |  Philip IV of Spain  |    | 
  | 1 March 1625  |  Peter Wyche  |  Charles I of England  |  Philip IV of Spain  |  30 April 1626  | 
  | 11 August 1628  |  Endymion Porter  |  Charles I of England  |  Philip IV of Spain  |  5 January 1629  | 
  | 1 July 1629  |  Francis Cottington, 1st Baron Cottington  |  Charles I of England  |  Philip IV of Spain  |  20 April 1631  | 
  | 18 December 1630  |  Arthur Hopton  |  Charles I of England  |  Philip IV of Spain  |  23 April 1636  | 
  | 13 July 1634  |  John Taylor  |  Charles I of England  |  Philip IV of Spain  |  24 May 1635  | 
  | 26 December 1634  |  Walter Aston, 1st Lord Aston of Forfar  |  Charles I of England  |  Philip IV of Spain  |  31 July 1638  | 
  | April 1638  |  Sir Richard Fanshawe, 1st Baronet  |  Charles I of England  |  Philip IV of Spain  |  10 June 1638  | 
  | 21 March 1638  |  Arthur Hopton  |  Charles I of England  |  Philip IV of Spain  |  December 1645  | 
  | 25 January 1650  |  Anthony Ascham  |  English Council of State  |  Philip IV of Spain  |  27 May 1650  | 
  | 27 May 1650  |  George Fisher  |  English Council of State  |  Philip IV of Spain  |  26 September 1651  | 
  | 1654  |  Anglo-Spanish War (1654-1660)  |  English Council of State  |  Philip IV of Spain  |  1660  | 
  | 20 February 1666  |  Edward Montagu, 1st Earl of Sandwich  |  Charles II of England  |  Charles II of Spain  |  11 October 1668  | 
  | 26 February 1666  |  Robert Southwell  |  Charles II of England  |  Charles II of Spain  |  22 June 1666  | 
  | 10 July 1668  |  Sir John Werden, 1st Baronet  |  Charles II of England  |  Charles II of Spain  |  10 June 1668  | 
  | 10 July 1668  |  William Godolphin  |  Charles II of England  |  Charles II of Spain  |  10 June 1668  | 
  | 21 November 1671  |  Robert Spencer, 2nd Earl of Sunderland  |  Charles II of England  |  Charles II of Spain  |  20 May 1672  | 
  | 29 June 1677  |  Ignatius White  |  Charles II of England  |  Charles II of Spain  |  October 1677  | 
  | 12 June 1679  |  Sir Henry Goodricke, 2nd Baronet[17]  |  Charles II of England  |  Charles II of Spain  |  27 March 1683  | 
  | 10 December 1682  |  Peter Lefett  |  Charles II of England  |  Charles II of Spain  |  16 November 1685  | 
  | 13 May 1685  |  Charles Granville, 2nd Earl of Bath  |  Charles II of England  |  Charles II of Spain  |  December 1688  | 
  | 13 May 1685  |  John Stafford  |  James II of England  |  Charles II of Spain  |  December 1688  | 
  | May 1689  |  Viscount Dursley  |  Mary II of England  |  Charles II of Spain  |  August 1689  | 
  | 1689  |  Alexander Stanhope[18]  |  Mary II of England  |  Charles II of Spain  |  1699  | 
  | 1699  |  Francis Schonenberg[19]  |  William III of England  |  Charles II of Spain  |  1702  | 
  | 1702  |  War of the Spanish Succession  |  William III of England  |  Philip V of Spain  |  1702  | 
  | 1705  |  Mitford Crowe[20]  |  Anne, Queen of Great Britain  |  Philip V of Spain  |  1706  | 
  | 1705  |  Paul Methuen  |  Anne, Queen of Great Britain  |  Philip V of Spain  |  1706  | 
  | 1706  |  Charles Mordaunt, 3rd Earl of Peterborough,  James Stanhope, 1st Earl Stanhope (joint envoys)[21][22]    |  Anne, Queen of Great Britain  |  Charles III of Hungary  |  {1707   {1710    | 
  | 1711  |  John Campbell, 2nd Duke of Argyll[23]  |  Anne, Queen of Great Britain  |  Charles III of Hungary  |  1712  | 
  | 1712  |  Robert Sutton, 2nd Baron Lexinton[24]  |  Anne, Queen of Great Britain  |  Philip V of Spain  |  1713  | 
  | 1713  |  Robert Benson, 1st Baron Bingley[25]  |  Anne, Queen of Great Britain  |  Philip V of Spain  |  1714  | 
  | 1714  |  Paul Methuen  |  Anne, Queen of Great Britain  |  Philip V of Spain  |  1715  | 
  | 1715  |  George Dodington, 1st Baron Melcombe  |  George I of Great Britain  |  Philip V of Spain  |  1717  | 
  | 1717  |  John Chetwynd, 2nd Viscount Chetwynd  |  George I of Great Britain  |  Philip V of Spain  |  1718  | 
  | 1718  |  War of the Quadruple Alliance  |  George I of Great Britain  |  Philip V of Spain  |  1720  | 
  | 1720  |  Luke Schaub  |  George I of Great Britain  |  Philip V of Spain  |  1720  | 
  | 1720  |  William Stanhope, 1st Earl of Harrington  |  George I of Great Britain  |  Philip V of Spain  |  1727  | 
  | 1727  |  Anglo-Spanish War (1727–29)  |  George I of Great Britain  |  Philip V of Spain  |    | 
  | 1729  |  Benjamin Keene  |  George II of Great Britain  |  Philip V of Spain  |  1739  | 
  | 1739  |  War of Jenkins' Ear  |  George II of Great Britain  |  Philip V of Spain  |  1748  | 
  | 1748  |  Sir Benjamin Keene  |  George II of Great Britain  |  Ferdinand VI of Spain  |  1757  | 
  | 1758  |  George Hervey, 2nd Earl of Bristol  |  George II of Great Britain  |  Ferdinand VI of Spain  |  1761  | 
  | 1761  |  Anglo-Spanish War (1761)  |  George III of the United Kingdom  |  Charles III of Spain  |  1763  | 
  | 19 February 1763  |  John Montagu, 4th Earl of Sandwich  |  George III of the United Kingdom  |  Charles III of Spain  |    | 
  | 1763  |  William Nassau de Zuylestein, 4th Earl of Rochford[26]  |  George III of the United Kingdom  |  Charles III of Spain  |  1766  | 
  | 1766  |  Sir James Gray, 2nd Baronet[18][27]  |  George III of the United Kingdom  |  Charles III of Spain  |  1769  | 
  | 1770  |  George Pitt, 1st Baron Rivers[28]  |  George III of the United Kingdom  |  Charles III of Spain  |  1771  | 
  | 1771  |  James Harris[29]  |  George III of the United Kingdom  |  Charles III of Spain  |    | 
  | 1771  |  Thomas Robinson, 2nd Baron Grantham  |  George III of the United Kingdom  |  Charles III of Spain  |  1779  | 
  | 1779  |  Anglo-Spanish War (1779-1783)  |  George III of the United Kingdom  |  Charles III of Spain  |  1783  | 
  | 1783  |  John Crichton-Stuart, 1st Marquess of Bute  |  George III of the United Kingdom  |  Charles III of Spain  |    | 
  | 1783  |  Robert Liston  |  George III of the United Kingdom  |  Charles III of Spain  |  1788  | 
  | 1784  |  Philip Stanhope, 5th Earl of Chesterfield  |  George III of the United Kingdom  |  Charles III of Spain  |  1785  | 
  | 1788  |  William Eden, 1st Baron Auckland[18][30]  |  George III of the United Kingdom  |  Charles IV of Spain  |  1790  | 
  | 1790  |  Alleyne FitzHerbert, 1st Baron St Helens  |  George III of the United Kingdom  |  Charles IV of Spain  |  1794  | 
  | 1794  |  Francis James Jackson  |  George III of the United Kingdom  |  Charles IV of Spain  |  1795  | 
  | 1795  |  John Crichton-Stuart, 1st Marquess of Bute  |  George III of the United Kingdom  |  Charles IV of Spain  |  1796  | 
  | 1796  |    |  George III of the United Kingdom  |  Charles IV of Spain  |  1802  | 
  | 1802  |  John Hookham Frere  |  George III of the United Kingdom  |  Charles IV of Spain  |  1804  | 
  | 1808  |  Charles Stuart  |  George III of the United Kingdom  |  Ferdinand VII of Spain  |  1808  | 
  | 1808  |  John Hookham Frere  |  George III of the United Kingdom  |  Ferdinand VII of Spain  |  1808  | 
  | 1809  |  Richard Wellesley, 1st Marquess Wellesley  |  George III of the United Kingdom  |  Ferdinand VII of Spain  |  1809  | 
  | 1810  |  Henry Wellesley  |  George III of the United Kingdom  |  Ferdinand VII of Spain  |  1821  | 
  | 1822  |  William à Court, 1st Baron Heytesbury  |  George IV of the United Kingdom  |  Ferdinand VII of Spain  |    | 
  | 1825  |  Frederick Lamb, 3rd Viscount Melbourne  |  George IV of the United Kingdom  |  Ferdinand VII of Spain  |    | 
  | 5 December 1827  |  George Bosanquet  |  George IV of the United Kingdom  |  Ferdinand VII of Spain  |  1830  | 
  | 1830  |  Henry Unwin Addington  |  George IV of the United Kingdom  |  Ferdinand VII of Spain  |  1833  | 
  | 1833  |  George Villiers, 4th Earl of Clarendon  |  William IV of the United Kingdom  |  Isabella II of Spain  |  1839  | 
  | 1839  |  George Jerningham  |  Queen Victoria  |  Isabella II of Spain  |    | 
  | 1840  |  Sir Arthur Ingram Aston  |  Queen Victoria  |  Isabella II of Spain  |  1843  | 
  | 1843  |  George Jerningham  |  Queen Victoria  |  Isabella II of Spain  |    | 
  | 1844  |  Henry Bulwer, 1st Baron Dalling and Bulwer  |  Queen Victoria  |  Isabella II of Spain  |  19 May 1848  | 
  | 19 May 1848  |  Revolutions of 1848  |  Queen Victoria  |  Isabella II of Spain  |  1850  | 
  | 1850  |  John Hobart Caradoc, 2nd Baron Howden  |  Queen Victoria  |  Isabella II of Spain  |    | 
  | 1858  |  Sir Andrew Buchanan, 1st Baronet  |  Queen Victoria  |  Isabella II of Spain  |    | 
  | 1860  |  John Fiennes Twisleton Crampton  |  Queen Victoria  |  Isabella II of Spain  |    | 
  | 1869  |  Austen Henry Layard  |  Queen Victoria  |  Francisco Serrano, 1st Duke of la Torre  |    | 
  | 1878  |  Sir Lionel Sackville-West  |  Queen Victoria  |  Alfonso XII of Spain  |    | 
  | 1881  |  Robert Morier  |  Queen Victoria  |  Alfonso XII of Spain  |    | 
  | 1884  |  Francis Clare Ford  |  Queen Victoria  |  Alfonso XII of Spain  |  1887  | 
  | 1887  |  Francis Clare Ford  |  Queen Victoria  |  Alfonso XIII of Spain  |  1892  | 
  | 1892  |  Henry Drummond Wolff  |  Queen Victoria  |  Alfonso XIII of Spain  |  1900  | 
  | 1900  |  Henry Mortimer Durand  |  Queen Victoria  |  Alfonso XIII of Spain  |  1903  | 
  | 1903  |  Edwin Henry Egerton  |  Edward VII  |  Alfonso XIII of Spain  |  1904  | 
  | 1904  |  Arthur Nicolson, 1st Baron Carnock  |  Edward VII  |  Alfonso XIII of Spain  |  1905  | 
  | February 1906  |  Maurice William Ernest de Bunsen  |  Edward VII  |  Alfonso XIII of Spain  |  1913  | 
  | 1913  |  Arthur Henry Hardinge  |  George V  |  Alfonso XIII of Spain  |    | 
  | 1919  |  Esme Howard, 1st Baron Howard of Penrith  |  George V  |  Alfonso XIII of Spain  |  1919  | 
  | 1924  |  Sir Horace Rumbold, 9th Baronet  |  George V  |  Alfonso XIII of Spain  |    | 
  | 1928  |  George Dixon Grahame  |  George V  |  Alfonso XIII of Spain  |    | 
  | 1935  |  Henry Chilton  |  George V  |  Niceto Alcalá-Zamora  |    | 
  | 27 February 1939  |  Maurice Peterson  |  George V  |  Francisco Franco  |  1940  | 
  | 1940  |  Samuel Hoare, 1st Viscount Templewood  |  George VI  |  Francisco Franco  |    | 
  | 1945  |  Sir Victor Mallet  |  George VI  |  Francisco Franco  |    | 
  | 1946  |  Sir Douglas Howard  |  George VI  |  Francisco Franco  |  1949  | 
  | 10 November 1949  |  Robert Hankey, 2nd Baron Hankey  |  George VI  |  Francisco Franco  |  1950  | 
  | 1951  |  Sir John Balfour  |  George VI  |  Francisco Franco  |  1954  | 
  | 1954  |  Sir William Ivo Mallet  |  Elizabeth II  |  Francisco Franco  |  1960  | 
  | 1960  |  Sir George Labouchère  |  Elizabeth II  |  Francisco Franco  |    | 
  | 1966  |  Sir Alan Meredith Williams  |  Elizabeth II  |  Francisco Franco  |    | 
  | 1969  |  Sir John Russell  |  Elizabeth II  |  Francisco Franco  |    | 
  | 1974  |  Sir Charles Wiggin  |  Elizabeth II  |  Francisco Franco  |  1977  | 
  | 1977  |  Sir Antony Acland  |  Elizabeth II  |  Juan Carlos I of Spain  |    | 
  | 1980  |  Sir Richard Parsons  |  Elizabeth II  |  Juan Carlos I of Spain  |    | 
  | 1984  |  Lord Nicholas Gordon-Lennox  |  Elizabeth II  |  Juan Carlos I of Spain  |  1989  | 
  | 1989  |  Sir Robin Fearn  |  Elizabeth II  |  Juan Carlos I of Spain  |    | 
  | 1994  |  David Brighty  |  Elizabeth II  |  Juan Carlos I of Spain  |    | 
  | 1998  |  Sir Peter Torry  |  Elizabeth II  |  Juan Carlos I of Spain  |  1998  | 
  | 2003  |  Sir Stephen Wright  |  Elizabeth II  |  Juan Carlos I of Spain  |  2007  | 
  | 2007  |  Dame Denise Holt  |  Elizabeth II  |  Juan Carlos I of Spain  |  2009  | 
  | 2009  |  Giles Paxman  |  Elizabeth II  |  Juan Carlos I of Spain  |  2013  | 
  | 2013  |  Simon Manley[31]  |  Elizabeth II  |  Juan Carlos I of Spain  King Felipe VI of Spain    |  2019  | 
  | 2019  |  Hugh Elliott[32]  |  Elizabeth II  Charles III    |  King Felipe VI of Spain  |  2024  | 
  | 2024  |  Sir Alex Ellis[33][1]  |  Charles III  |  King Felipe VI of Spain  |    |