Melicopidine

Melicopidine
Names
	Preferred IUPAC name 4,11-dimethoxy-5-methyl-[1,3]dioxolo[4,5-b]acridin-10-one
Identifiers
CAS Number	475-91-2 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:167835;
ChEMBL	ChEMBL1864207;
ChemSpider	61375;
ECHA InfoCard	100.006.821
EC Number	207-502-0;
PubChem CID	68060;
UNII	38R6F4CJ0M;
CompTox Dashboard (EPA)	DTXSID3075410 ;
	InChI InChI=1S/C17H15NO5/c1-18-10-7-5-4-6-9(10)13(19)11-12(18)15(21-3)17-16(14(11)20-2)22-8-23-17/h4-7H,8H2,1-3H3 Key: TZZNUDMEMFBPQI-UHFFFAOYSA-N;
	SMILES CN1C2=CC=CC=C2C(=O)C3=C1C(=C4C(=C3OC)OCO4)OC;
Properties
Chemical formula	C17H15NO5
Molar mass	313.309 g·mol−1
Hazards
	Lethal dose or concentration (LD, LC):
LDLo (lowest published)	200 mg/kg (mouse)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Melicopidine is an alkaloid. Its formula is C₁₇H₁₅NO₅. It, along with melicopine and melicopicine, is named for the Australian rutaceae (Melicope fareana) from which it was first isolated.^[2]

Occurrence

As an alkaloid, melicopidine naturally occurs in and has been isolated from Medicosma fareana^[3] and Sarcomelicope megistophylla^[4] in addition to Melicope fareana.^[2]

References

^ Svoboda GH, Kattau RW (1967). "Alkaloids of Acronychia Baueri (Baurella australiana) III". Lloydia. 30: 364.
^ ^a ^b Crow W, Price J (1949). "Alkaloids of the Australian Rutaceae: Melicope fareana. II. Preliminary Examination of Melicopine, Melicopidine, and Melicopicine". Australian Journal of Chemistry. 2 (2): 255. Bibcode:1949AuSRA...2..255C. doi:10.1071/CH9490255. ISSN 0004-9425.
^ Habtemariam S, Waterman PG, Hartley T (September 1996). "Fareanine and fareanol from leaves of Medicosma fareana". Phytochemistry. 43 (1): 291–294. Bibcode:1996PChem..43..291H. doi:10.1016/0031-9422(96)00220-8.
^ Mitaku S, Fokialakis N, Magiatis P, Tillequin F (February 2007). "Alkaloids from Sarcomelicope megistophylla". Fitoterapia. 78 (2): 169–170. doi:10.1016/j.fitote.2006.10.003. PMID 17207940.

[1] Svoboda GH, Kattau RW (1967). "Alkaloids of Acronychia Baueri (Baurella australiana) III". Lloydia. 30: 364.

[:0-2] Crow W, Price J (1949). "Alkaloids of the Australian Rutaceae: Melicope fareana. II. Preliminary Examination of Melicopine, Melicopidine, and Melicopicine". Australian Journal of Chemistry. 2 (2): 255. Bibcode:1949AuSRA...2..255C. doi:10.1071/CH9490255. ISSN 0004-9425.

[3] Habtemariam S, Waterman PG, Hartley T (September 1996). "Fareanine and fareanol from leaves of Medicosma fareana". Phytochemistry. 43 (1): 291–294. Bibcode:1996PChem..43..291H. doi:10.1016/0031-9422(96)00220-8.

[4] Mitaku S, Fokialakis N, Magiatis P, Tillequin F (February 2007). "Alkaloids from Sarcomelicope megistophylla". Fitoterapia. 78 (2): 169–170. doi:10.1016/j.fitote.2006.10.003. PMID 17207940.

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