New methylene blue

New methylene blue
Identifiers
CAS Number	1934-16-3 ;
3D model (JSmol)	Interactive image;
ChemSpider	16736255 ;
ECHA InfoCard	100.026.833
PubChem CID	73518;
UNII	5GCZ112BCN ;
	InChI InChI=1S/C18H22N3S.ClH/c1-5-19-13-9-17-15(7-11(13)3)21-16-8-12(4)14(20-6-2)10-18(16)22-17;/h7-10,19-20H,5-6H2,1-4H3;1H/q+1;/p-1 Key: NZYCYASKVWSANA-UHFFFAOYSA-M ; InChI=1/C18H22N3S.ClH/c1-5-19-13-9-17-15(7-11(13)3)21-16-8-12(4)14(20-6-2)10-18(16)22-17;/h7-10,19-20H,5-6H2,1-4H3;1H/q+1;/p-1 Key: NZYCYASKVWSANA-REWHXWOFAR;
	SMILES [Cl-].Cc1cc2nc3cc(C)c(cc3[s+]c2cc1NCC)NCC;
Properties
Chemical formula	C18H22N3S:SCl ZnCl2
Molar mass	484.22 g/mol
Melting point	239 °C (462 °F; 512 K)
Boiling point	Decomposes
Hazards
	GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H302, H312, H332
Precautionary statements	P261, P264, P270, P271, P280, P301+P317, P302+P352, P304+P340, P317, P321, P330, P362+P364, P501
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

New methylene blue (also NMB) is an organic compound of the thiazine class of heterocycles. It is used as a stain and as an antimicrobial agent. It is classified as an azine dye, and the chromophore is a cation, the anion is often unspecified.^[1]

Applications

NMB is a staining agent used in diagnostic cytopathology and histopathology, typically for staining immature red blood cells. It is a supravital stain.^[2] It is closely related to methylene blue, an older stain in wide use.

New methylene blue is toxic. Skin contact or inhalation should be avoided.

^ Vennerstrom, Jonathan L.; Makler, Michael T.; Angerhofer, Cidy K.; Williams, Jean A. "Antimalarial dyes revisited: xanthenes, azines, oxazines, and thiazine" Antimicrobial Agents and Chemotherapy (1995), 39(12), 2671–7. doi:10.1128/AAC.39.12.2671.
^ "Reticulocyte Count" (PDF). Prentice-Hall.