Dibutepinephrine

Dibutepinephrine
Clinical data
Other namesDiisobutyrylepinephrine; Diisobutanoylepinephrine; Diisobutyryladrenaline; Diisobutanoyladrenaline
Drug classSympathomimetic
Identifiers
  • [4-[(1R)-1-hydroxy-2-(methylamino)ethyl]-2-(2-methylpropanoyloxy)phenyl] 2-methylpropanoate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC17H25NO5
Molar mass323.389 g·mol−1
3D model (JSmol)
  • CC(C)C(=O)OC1=C(C=C(C=C1)[C@H](CNC)O)OC(=O)C(C)C
  • InChI=1S/C17H25NO5/c1-10(2)16(20)22-14-7-6-12(13(19)9-18-5)8-15(14)23-17(21)11(3)4/h6-8,10-11,13,18-19H,9H2,1-5H3/t13-/m0/s1
  • Key:XUROVJXCRSDXKR-ZDUSSCGKSA-N

Dibutepinephrine (INNTooltip International Nonproprietary Name; USANTooltip United States Adopted Name; also known as diisobutyrylepinephrine) is a sympathomimetic drug which has not been marketed at this time.[1][2] It is the 3,4-O-diisobutyryl ester and hence a prodrug of epinephrine (adrenaline).[1][2][3]

See also

References

  1. ^ a b "Proposed INN: List 128 International Nonproprietary Names for Pharmaceutical Substances (INN)" (PDF). WHO Drug Information. 36 (4). 2022. dibutepinephrinum dibutepinephrine 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]-1,2- phenylene bis(2-methylpropanoate) sympathomimetic [...] C17H25NO5 2735735-23-4
  2. ^ a b "Dibutepinephrine hydrochloride". Inxight Drugs. Retrieved 27 February 2025.
  3. ^ WO 2023/069733, Wargacki SP, Kainthan RK, Buono V, Schobel AM, Koons M, Goodrich M, Tsodikov G, "Pharmaceutical compositions with enhanced stability profiles", published 27 April 2023, assigned to Aquestive Therapeutics, Inc. 
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