Incumbent Democrat Neil Abercrombie defeated Republican Richard Hough. This district covers the southern portion of the island, city, and county of Honolulu.
Incumbent Democrat Ed Case decided to retire, in order to run for the U.S. Senate. Democrat Mazie Hirono, a former Lieutenant Governor, defeated Republican Bob Hogue, a State Senator. She became the first Buddhist to be elected to the U.S. Congress.
^ ab"2006 House Ratings". House Ratings. The Rothenberg Political Report. November 6, 2006. Archived from the original on November 7, 2006. Retrieved November 20, 2023.
^ ab"2006 House". Sabato's Crystal Ball. November 6, 2006. Archived from the original on November 10, 2006. Retrieved November 20, 2023.