The 2022 Cal Poly Mustangs football team represented California Polytechnic State University, San Luis Obispo as member of the Big Sky Conference during the 2022 NCAA Division I FCS football season. Led by Beau Baldwin in his third and final season as head coach, the Mustangs compiled an overall record of 2–9 with a mark of 1–7 in conference play, tying for 11th place in the Big Sky. Cal poly played home games at Mustang Stadium in San Luis Obispo, California. 
  Schedule
 | Date | Time | Opponent | Site | TV | Result | Attendance | 
|---|
|  | 7:30 p.m. | at Fresno State* |  | FS1 | L 7–35 | 36,011 | 
 | September 10 | 2:05 p.m. | San Diego* |  | ESPN+ | W 28–27 | 6,782 | 
 | September 17 | 11:00 a.m. | at South Dakota* |  | ESPN+ | L 21–38 | 6,812 | 
 | October 1 | 5:05 p.m. | No. 5 Sacramento State  | Alex G. Spanos StadiumSan Luis Obispo, CA
 | ESPN+ | L 21–49 | 8,184 | 
 | October 8 | 1:00 p.m. | at Northern Arizona |  | ESPN+ | L 29–31 | 9,417 | 
 | October 15 | 12:05 p.m. | at Idaho State |  | ESPN+ | L 31–40 | 5,921 | 
 | October 22 | 5:05 p.m. | Eastern Washington | Alex G. Spanos StadiumSan Luis Obispo, CA
 | ESPN+ | L 10–17 | 8,357 | 
 | October 29 | 4:00 p.m. | at UC Davis |  | ESPN+ | L 17–59 | 8,189 | 
 | November 5 | 5:00 p.m. | at No. 16 Montana |  | ESPN+ | L 0–57 | 25,684 | 
 | November 12 | 5:05 p.m. | No. 3 Montana State | Mustang Memorial FieldSan Luis Obispo, CA
 | ESPN+ | L 28–72 | 5,369 | 
 | November 19 | 5:05 p.m. | Portland State | Mustang Memorial FieldSan Luis Obispo, CA
 | ESPN+ | W 49–42 | 5,168 | 
 | *Non-conference game HomecomingRankings from STATS Poll released prior to the gameAll times are in Pacific time
 | 
 [1][2][3] 
 
 Preseason
 Polls
 On July 25, 2022, during the virtual Big Sky Kickoff, the Mustangs were predicted to finish tenth in the Big Sky by both the coaches and media.[4] 
  Coaches poll    | Predicted finish | Team | Votes (1st place) | 
    | 1 | Montana | 111 (3) | 
  | 2 | Sacramento State | 110 (4) | 
  | 3 | Montana State | 109 (5) | 
  | 4 | Weber State | 84 | 
  | 5 | UC Davis | 82 | 
  | 6 | Eastern Washington | 76 | 
  | 7 | Northern Arizona | 62 | 
  | 8 | Idaho | 45 | 
  | 9 | Portland State | 42 | 
  | 10 | Cal Poly | 33 | 
  | T-11 | Idaho State | 19 | 
  | T-11 | Northern Colorado | 19 | 
  Media poll    | Predicted finish | Team | Votes (1st place) | 
    | 1 | Montana | 356 (14) | 
  | 2 | Montana State | 352 (13) | 
  | 3 | Sacramento State | 335 (4) | 
  | 4 | Weber State | 261 | 
  | 5 | UC Davis | 255 (1) | 
  | 6 | Eastern Washington | 236 | 
  | 7 | Northern Arizona | 191 | 
  | 8 | Portland State | 146 | 
  | 9 | Idaho | 142 | 
  | 10 | Cal Poly | 85 | 
  | 11 | Northern Colorado | 71 | 
  | 12 | Idaho State | 66 | 
 Preseason All–Big Sky team
 The Mustangs did not have any players selected to the preseason all-Big Sky team.[5] 
 Game summaries
 At Fresno State
    Game One – Cal Poly Mustangs (0–0) at Fresno State Bulldogs (0–0)
  at Bulldog Stadium • Fresno, CA 
 - Date: Thursday, September 1, 2022
- Game time: 7:30 p.m. PST
- Game weather: Sunny • Temperature: 102 °F (39 °C) • Wind: NW 10 mph
- Game attendance: 36,011
- Referee: Christian Watson
- TV announcers (FS1): Eric Collins (play-by-play) & Devin Gardner (analyst)
- Pregame line: Fresno State −42.0
     | Game information | 
  | First quarter
 (8:37) FRES – Jordan Mims 1-yard run, Abraham Montano kick (Drive: 9 plays, 68 yards, 4:40; Fresno State 7–0)(3:54) FRES – Nikko Remigio 13-yard run, Abraham Montano kick (Drive: 9 plays, 93 yards, 3:49; Fresno State 14–0)(0:29) FRES – Jordan Mims 1-yard run, Abraham Montano kick (Drive: 6 plays, 75 yards, 2:06; Fresno State 21–0)
 Second quarter
 (11:54) CP – Bryson Allen 9-yard pass from Jaden Jones, Jaden Ohlsen kick (Drive: 9 plays, 75 yards, 3:35; Fresno State 21–7)
 Third quarter
 (8:53) FRES – Jordan Mims 18-yard pass from Jake Haener, Abraham Montano kick (Drive: 3 plays, 34 yards, 1:05; Fresno State 28–7)
 Fourth quarter
 (8:53) FRES – Raymond Pauwels 8-yard pass from Jake Haener, Abraham Montano kick (Drive: 16 plays, 95 yards, 6:52; Fresno State 35–7)
 | 
     | Statistics | CP | FRES | 
  | First downs | 17 | 32 | 
  | Plays–yards | 68–317 | 75–549 | 
  | Rushes–yards | 30–106 | 33–175 | 
  | Passing yards | 211 | 370 | 
  | Passing: comp–att–int | 20–38–0 | 35–42–0 | 
  | Time of possession | 26:19 | 33:41 | 
 
   | Team | Category | Player | Statistics | 
  | Cal Poly | Passing | Jaden Jones | 20/38, 211 yards, TD | 
  | Rushing | Jaden Jones | 9 carries, 59 yards | 
  | Receiving | Chris Coleman | 3 receptions 74 yards | 
  | Fresno State | Passing | Jake Haener | 35/41, 370 yards, 2 TD | 
  | Rushing | Jordan Mims | 15 carries, 76 yards, 2 TD | 
  | Receiving | Nikko Remigio | 9 receptions, 100 yards | 
  San Diego
    |  |  |  |  |  | Total | 
  | Toreros | 7 | 10 | 7 | 3 | 27 | 
  | Mustangs | 0 | 7 | 7 | 14 | 28 | 
   At South Dakota
    |  |  |  |  |  | Total | 
  | Mustangs | 7 | 0 | 0 | 14 | 21 | 
  | Coyotes | 21 | 0 | 0 | 17 | 38 | 
   No. 5 Sacramento State
    |  |  |  |  |  | Total | 
  | No. 5 Hornets | 7 | 14 | 14 | 14 | 49 | 
  | Mustangs | 0 | 0 | 7 | 14 | 21 | 
   At Northern Arizona
    |  |  |  |  |  | Total | 
  | Mustangs | 6 | 14 | 0 | 9 | 29 | 
  | Lumberjacks | 14 | 7 | 7 | 3 | 31 | 
   At Idaho State
    |  |  |  |  |  | Total | 
  | Mustangs | 7 | 0 | 10 | 14 | 31 | 
  | Bengals | 14 | 10 | 13 | 3 | 40 | 
   Eastern Washington
    |  |  |  |  |  | Total | 
  | Eagles | 10 | 0 | 0 | 7 | 17 | 
  | Mustangs | 7 | 3 | 0 | 0 | 10 | 
   At UC Davis
    |  |  |  |  |  | Total | 
  | Mustangs | 0 | 17 | 0 | 0 | 17 | 
  | Aggies | 14 | 17 | 14 | 14 | 59 | 
   At No. 16 Montana
    |  |  |  |  |  | Total | 
  | Mustangs | 0 | 0 | 0 | 0 | 0 | 
  | No. 16 Grizzlies | 14 | 17 | 13 | 13 | 57 | 
   No. 3 Montana State
    |  |  |  |  |  | Total | 
  | No. 3 Bobcats | 24 | 27 | 14 | 7 | 72 | 
  | Mustangs | 0 | 14 | 14 | 0 | 28 | 
   Portland State
    |  |  |  |  |  | Total | 
  | Vikings | 14 | 7 | 0 | 21 | 42 | 
  | Mustangs | 0 | 28 | 7 | 14 | 49 | 
   Roster
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