Diphenylmethylpiperazine
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| Names | |
|---|---|
| Preferred IUPAC name 1-(Diphenylmethyl)piperazine | |
| Other names 1-benzhydrylpiperazine; Norcyclizine | |
| Identifiers | |
3D model (JSmol) | |
| ChemSpider | |
| ECHA InfoCard | 100.011.516 |
PubChem CID | |
| UNII | |
CompTox Dashboard (EPA) | |
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| Properties | |
| C17H20N2 | |
| Molar mass | 252.35 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references | |
Diphenylmethylpiperazine, also known as benzhydrylpiperazine, is a chemical compound and piperazine derivative. It features a piperazine ring with a benzhydryl (diphenylmethyl) group bound to one of the nitrogens.[1][2] Cyclizine, an antihistamine and anticholinergic drug used to treat motion sickness, is the methylated derivative of diphenylmethylpiperazine.
References
- ^ Calderon SN (2011). "Nonpeptidic delta (delta) opioid agonists and antagonists of the diarylmethylpiperazine class: what have we learned?". Top Curr Chem. 299: 121–140. PMID 21630509.
- ^ Kaczor A, Matosiuk D (2002). "Non-peptide opioid receptor ligands - recent advances. Part I - agonists". Curr Med Chem. 9 (17): 1567–1589. PMID 12171553.